TY - GEN
T1 - A high efficient fluidic microchannel for cell immobilization with controllable quantity
AU - Xiaoqing, Tang
AU - Xiaoming, Liu
AU - Pengyun, Li
AU - Yuqing, Lin
AU - Kojima, Masaru
AU - Qiang, Huang
AU - Arai, Tatsuo
N1 - Publisher Copyright:
Copyright© (2018) by Chemical and Biological Microsystems Society.All rights reserved.
PY - 2018
Y1 - 2018
N2 - Cell immobilization is an essential process in the cell analysis, cell measurement and cell surgery. Single-cell analysis and multi-cell communication impose different requirements on the number of cells which need immobilized. Advances in microchannel provide us a great tool in cell immobilization, since the applied harmless fluidic field force and controllable closed fluidic environment. In this paper, we propose a high efficient microchannel for trapping cells with controllable quantity, which uses the passive fluidic force and is based on “least flow resistance path” principle. With this presented microchannel design, immobilization of single cell and dual cells have been achieved with success rates of 96% and 95% respectively. Therefore, we expect that the high efficient microchannel can be of great importance for the biological research.
AB - Cell immobilization is an essential process in the cell analysis, cell measurement and cell surgery. Single-cell analysis and multi-cell communication impose different requirements on the number of cells which need immobilized. Advances in microchannel provide us a great tool in cell immobilization, since the applied harmless fluidic field force and controllable closed fluidic environment. In this paper, we propose a high efficient microchannel for trapping cells with controllable quantity, which uses the passive fluidic force and is based on “least flow resistance path” principle. With this presented microchannel design, immobilization of single cell and dual cells have been achieved with success rates of 96% and 95% respectively. Therefore, we expect that the high efficient microchannel can be of great importance for the biological research.
KW - Controllable quantity
KW - Efficient microchannel
KW - Immobilization
UR - http://www.scopus.com/inward/record.url?scp=85079853049&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85079853049
T3 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
SP - 452
EP - 454
BT - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PB - Chemical and Biological Microsystems Society
T2 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Y2 - 11 November 2018 through 15 November 2018
ER -