摘要
The biocatalytic desymmetrization of racemates of chiral compounds is the focus, difficulty and hotspot in the field of biological and organic synthesis currently, and it is also an important way to prepare optically pure chiral compounds. In this paper, the methods for biocatalytic desymmetrization of chiral compounds developed in recent years are summarized as desymmetrization by stereoinversion, linear desymmetrization, cyclic desymmetrization, enantioconvergent process desymmetrization and one-step desymmetrization. The principles, characteristics and application progress of these methods are respectively introduced and their future development trends are prospected.
投稿的翻译标题 | Research Progress in Biocatalytic Desymmetrization of Racemic Compounds |
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源语言 | 繁体中文 |
页(从-至) | 471-483 |
页数 | 13 |
期刊 | Journal of Molecular Catalysis |
卷 | 35 |
期 | 5 |
DOI | |
出版状态 | 已出版 - 10月 2021 |
关键词
- Biocatalysis
- Chiral compounds
- Desymmetrization
- Racemates
指纹
探究 '外消旋化合物生物催化去对称化研究进展' 的科研主题。它们共同构成独一无二的指纹。引用此
Su, Y. M., & Dai, D. Z. (2021). 外消旋化合物生物催化去对称化研究进展. Journal of Molecular Catalysis, 35(5), 471-483. https://doi.org/10.16084/j.issn1001-3555.2021.05.008