外消旋化合物生物催化去对称化研究进展

Ya Min Su, Da Zhang Dai*

*此作品的通讯作者

科研成果: 期刊稿件文献综述同行评审

摘要

The biocatalytic desymmetrization of racemates of chiral compounds is the focus, difficulty and hotspot in the field of biological and organic synthesis currently, and it is also an important way to prepare optically pure chiral compounds. In this paper, the methods for biocatalytic desymmetrization of chiral compounds developed in recent years are summarized as desymmetrization by stereoinversion, linear desymmetrization, cyclic desymmetrization, enantioconvergent process desymmetrization and one-step desymmetrization. The principles, characteristics and application progress of these methods are respectively introduced and their future development trends are prospected.

投稿的翻译标题Research Progress in Biocatalytic Desymmetrization of Racemic Compounds
源语言繁体中文
页(从-至)471-483
页数13
期刊Journal of Molecular Catalysis
35
5
DOI
出版状态已出版 - 10月 2021

关键词

  • Biocatalysis
  • Chiral compounds
  • Desymmetrization
  • Racemates

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引用此

Su, Y. M., & Dai, D. Z. (2021). 外消旋化合物生物催化去对称化研究进展. Journal of Molecular Catalysis, 35(5), 471-483. https://doi.org/10.16084/j.issn1001-3555.2021.05.008