Synthesis of new hyaluronic metal complexes and investigation of biological activity

Zhan Zhu*, Ya Li Wang, Yan Ping Yang, Shi Zhuo Xu, Jing Jing Dou, Bing Nan Guo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Several new hyaluronic metal complexes were synthesized with the sodium hyaluronate as raw material. The properties of synthesized complexes were characterized by IR, 1HNMR, EDX and elemental analysis. The preliminaries of anticancer activities in vitro on human uterine cancer cells demonstrate that a few of new hyaluronic metal complexes have better anticancer activity than that of the background sodium hyaluronate.

Original languageEnglish
Pages (from-to)1200-1204
Number of pages5
JournalBeijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology
Volume32
Issue number11
Publication statusPublished - Nov 2012

Keywords

  • Hyaluronic metal complexes
  • Sodium hyaluronate
  • Uterine cancer

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