Synthesis and crystal structure of (9s)-N-methyl-3-azabicyclo[3.3.1] nonan-9-yl (cyclopentyl)(hydroxy)(2-thienyl)acetate hydrochloride

Yan Qing Liu; He Liu; Bo Hua Zhong; Yu Lin Deng; Ke Liang Liu

doi:10.3184/030823405774309041

Synthesis and crystal structure of (9s)-N-methyl-3-azabicyclo[3.3.1] nonan-9-yl (cyclopentyl)(hydroxy)(2-thienyl)acetate hydrochloride

Yan Qing Liu, He Liu^*, Bo Hua Zhong, Yu Lin Deng, Ke Liang Liu

^*Corresponding author for this work

School of Medical and Technology

Research output: Contribution to journal › Article › peer-review

Abstract

(9s)-N-methyl-3-azabicyclo[3.3.1]nonan-9-yl (cyclopentyl)(hydroxy)(2- thienyl)acetate hydrochloride, a more effective muscarinic receptor antagonist, was synthesised and its crystal structure elucidated by X-ray crystallography.

Original language	English
Pages (from-to)	436-437
Number of pages	2
Journal	Journal of Chemical Research
Issue number	7
DOIs	https://doi.org/10.3184/030823405774309041
Publication status	Published - Jul 2005

Keywords

Crystal structure
Muscarinic receptor antagonist
Synthesis

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title = "Synthesis and crystal structure of (9s)-N-methyl-3-azabicyclo[3.3.1] nonan-9-yl (cyclopentyl)(hydroxy)(2-thienyl)acetate hydrochloride",

abstract = "(9s)-N-methyl-3-azabicyclo[3.3.1]nonan-9-yl (cyclopentyl)(hydroxy)(2- thienyl)acetate hydrochloride, a more effective muscarinic receptor antagonist, was synthesised and its crystal structure elucidated by X-ray crystallography.",

keywords = "Crystal structure, Muscarinic receptor antagonist, Synthesis",

author = "Liu, {Yan Qing} and He Liu and Zhong, {Bo Hua} and Deng, {Yu Lin} and Liu, {Ke Liang}",

year = "2005",

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doi = "10.3184/030823405774309041",

language = "English",

pages = "436--437",

journal = "Journal of Chemical Research",

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AU - Liu, Yan Qing

AU - Liu, He

AU - Zhong, Bo Hua

AU - Deng, Yu Lin

AU - Liu, Ke Liang

PY - 2005/7

Y1 - 2005/7

N2 - (9s)-N-methyl-3-azabicyclo[3.3.1]nonan-9-yl (cyclopentyl)(hydroxy)(2- thienyl)acetate hydrochloride, a more effective muscarinic receptor antagonist, was synthesised and its crystal structure elucidated by X-ray crystallography.

AB - (9s)-N-methyl-3-azabicyclo[3.3.1]nonan-9-yl (cyclopentyl)(hydroxy)(2- thienyl)acetate hydrochloride, a more effective muscarinic receptor antagonist, was synthesised and its crystal structure elucidated by X-ray crystallography.

KW - Crystal structure

KW - Muscarinic receptor antagonist

KW - Synthesis

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DO - 10.3184/030823405774309041

M3 - Article

AN - SCOPUS:23344450037

SN - 0308-2342

SP - 436

EP - 437

JO - Journal of Chemical Research

JF - Journal of Chemical Research

IS - 7

ER -

Synthesis and crystal structure of (9s)-N-methyl-3-azabicyclo[3.3.1] nonan-9-yl (cyclopentyl)(hydroxy)(2-thienyl)acetate hydrochloride

Abstract

Keywords

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