Supramolecular structured hydrogel preparation based on self-assemblies of photocurable star-shaped macromers with α-cyclodextrins

Hongliang Wei; Al Ying Zhang; Lijun Qian; Huaiqing Yu; Dandan Hou; Rongxin Qiu; Zeng Guo Feng

doi:10.1002/pola.20773

Supramolecular structured hydrogel preparation based on self-assemblies of photocurable star-shaped macromers with α-cyclodextrins

Hongliang Wei, Al Ying Zhang, Lijun Qian, Huaiqing Yu, Dandan Hou, Rongxin Qiu, Zeng Guo Feng^*

^*Corresponding author for this work

School of Material Science and Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

A new gelation process during self assemblies of methacryol terminated poly(L-lactide)-b-poly(ethylene glycol) (PLA-b-PEG) copolymers containing three or four arms with α-CDs was investigated. Hydroxyl-terminated star-shaped copolymers of PLA-b-PEG were synthesized in toluene by a ring-opening polymerization of LA with 3A-PEG or 4A-PEG as an initiator and Sn(Oct) ₂ as a catalyst. Soluble macromers bearing methacryloyl terminals were prepared through the reaction of PLA-b-PEG copolymers with methacrylic anhydride in toluene. The results showed that these gels can be photopolymerized, when exposed to ultraviolet light in the presence of a photoinitiator, to produce biodegradable supramolecular structured hydrogels.

Original language	English
Pages (from-to)	2941-2949
Number of pages	9
Journal	Journal of Polymer Science, Part A: Polymer Chemistry
Volume	43
Issue number	13
DOIs	https://doi.org/10.1002/pola.20773
Publication status	Published - 1 Jul 2005

Keywords

Cyclodextrins
Hydrogels
Photopolymerization
Star-shaped macromers

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title = "Supramolecular structured hydrogel preparation based on self-assemblies of photocurable star-shaped macromers with α-cyclodextrins",

abstract = "A new gelation process during self assemblies of methacryol terminated poly(L-lactide)-b-poly(ethylene glycol) (PLA-b-PEG) copolymers containing three or four arms with α-CDs was investigated. Hydroxyl-terminated star-shaped copolymers of PLA-b-PEG were synthesized in toluene by a ring-opening polymerization of LA with 3A-PEG or 4A-PEG as an initiator and Sn(Oct) 2 as a catalyst. Soluble macromers bearing methacryloyl terminals were prepared through the reaction of PLA-b-PEG copolymers with methacrylic anhydride in toluene. The results showed that these gels can be photopolymerized, when exposed to ultraviolet light in the presence of a photoinitiator, to produce biodegradable supramolecular structured hydrogels.",

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AU - Wei, Hongliang

AU - Zhang, Al Ying

AU - Qian, Lijun

AU - Yu, Huaiqing

AU - Hou, Dandan

AU - Qiu, Rongxin

AU - Feng, Zeng Guo

PY - 2005/7/1

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N2 - A new gelation process during self assemblies of methacryol terminated poly(L-lactide)-b-poly(ethylene glycol) (PLA-b-PEG) copolymers containing three or four arms with α-CDs was investigated. Hydroxyl-terminated star-shaped copolymers of PLA-b-PEG were synthesized in toluene by a ring-opening polymerization of LA with 3A-PEG or 4A-PEG as an initiator and Sn(Oct) 2 as a catalyst. Soluble macromers bearing methacryloyl terminals were prepared through the reaction of PLA-b-PEG copolymers with methacrylic anhydride in toluene. The results showed that these gels can be photopolymerized, when exposed to ultraviolet light in the presence of a photoinitiator, to produce biodegradable supramolecular structured hydrogels.

AB - A new gelation process during self assemblies of methacryol terminated poly(L-lactide)-b-poly(ethylene glycol) (PLA-b-PEG) copolymers containing three or four arms with α-CDs was investigated. Hydroxyl-terminated star-shaped copolymers of PLA-b-PEG were synthesized in toluene by a ring-opening polymerization of LA with 3A-PEG or 4A-PEG as an initiator and Sn(Oct) 2 as a catalyst. Soluble macromers bearing methacryloyl terminals were prepared through the reaction of PLA-b-PEG copolymers with methacrylic anhydride in toluene. The results showed that these gels can be photopolymerized, when exposed to ultraviolet light in the presence of a photoinitiator, to produce biodegradable supramolecular structured hydrogels.

KW - Cyclodextrins

KW - Hydrogels

KW - Photopolymerization

KW - Star-shaped macromers

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Supramolecular structured hydrogel preparation based on self-assemblies of photocurable star-shaped macromers with α-cyclodextrins

Abstract

Keywords

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