Abstract
The dehydrogenative synthesis of β-damascenone from β-damascone via the related allyl bromide intermediate was studied in depth. The requisite dehydrobromination thereof was found strongly solvent system dependent. Under respective conditions, the product was identified as dehydrogenation-derived a, 4-alkoxy-derived b and 4-oxo-derived c, accordingly. In addition, the conversion from b to a was successfully accomplished, thereby offering an alternative access (with one step more) to reach β-damascenone.
Original language | English |
---|---|
Pages (from-to) | 420-428 |
Number of pages | 9 |
Journal | Flavour and Fragrance Journal |
Volume | 31 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1 Nov 2016 |
Externally published | Yes |
Keywords
- allyl bromide
- dehydrobromination
- solvent effect
- substitution
- β-damascenone