Recent advances in antiviral nucleoside and nucleotide therapeutics

Claire Simons*, Qinpei Wu, Thet Thet Htar

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

58 Citations (Scopus)

Abstract

Recent developments in nucleoside/nucleotide therapeutics and antiviral drug targets are described covering progress in the development of nucleoside/nucleotide mimetics for the treatment of influenza virus, human immunodeficiency virus type 1, hepatitis B and C virus, herpes virus infections; including herpes simplex virus, cytomegalovirus and varicella zoster virus infections, and the highly pathogenic poxviruses (variola, vaccinia and mokey pox) and filoviruses (Ebola and Marburg).

Original languageEnglish
Pages (from-to)1191-1203
Number of pages13
JournalCurrent Topics in Medicinal Chemistry
Volume5
Issue number13
DOIs
Publication statusPublished - 2005

Keywords

  • Antisense oligonucleotides
  • Filovirus
  • Hepatitis B and C virus
  • Herpes virus
  • Human immunodeficiency virus
  • Influenza virus
  • Nucleoside/nucleotide therapeutics
  • Poxvirus
  • siRNA

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