TY - JOUR
T1 - Optoelectronic tweezers
T2 - a versatile toolbox for nano-/micro-manipulation
AU - Zhang, Shuailong
AU - Xu, Bingrui
AU - Elsayed, Mohamed
AU - Nan, Fan
AU - Liang, Wenfeng
AU - Valley, Justin K.
AU - Liu, Lianqing
AU - Huang, Qiang
AU - Wu, Ming C.
AU - Wheeler, Aaron R.
N1 - Publisher Copyright:
© 2022 The Royal Society of Chemistry.
PY - 2022/10/26
Y1 - 2022/10/26
N2 - The rapid development of micromanipulation technologies has opened exciting new opportunities for the actuation, selection and assembly of a variety of non-biological and biological nano/micro-objects for applications ranging from microfabrication, cell analysis, tissue engineering, biochemical sensing, to nano/micro-machines. To date, a variety of precise, flexible and high-throughput manipulation techniques have been developed based on different physical fields. Among them, optoelectronic tweezers (OET) is a state-of-art technique that combines light stimuli with electric field together by leveraging the photoconductive effect of semiconductor materials. Herein, the behavior of micro-objects can be directly controlled by inducing the change of electric fields on demand in an optical manner. Relying on this light-induced electrokinetic effect, OET offers tremendous advantages in micromanipulation such as programmability, flexibility, versatility, high-throughput and ease of integration with other characterization systems, thus showing impressive performance compared to those of many other manipulation techniques. A lot of research on OET have been reported in recent years and the technology has developed rapidly in various fields of science and engineering. This work provides a comprehensive review of the OET technology, including its working mechanisms, experimental setups, applications in non-biological and biological scenarios, technology commercialization and future perspectives.
AB - The rapid development of micromanipulation technologies has opened exciting new opportunities for the actuation, selection and assembly of a variety of non-biological and biological nano/micro-objects for applications ranging from microfabrication, cell analysis, tissue engineering, biochemical sensing, to nano/micro-machines. To date, a variety of precise, flexible and high-throughput manipulation techniques have been developed based on different physical fields. Among them, optoelectronic tweezers (OET) is a state-of-art technique that combines light stimuli with electric field together by leveraging the photoconductive effect of semiconductor materials. Herein, the behavior of micro-objects can be directly controlled by inducing the change of electric fields on demand in an optical manner. Relying on this light-induced electrokinetic effect, OET offers tremendous advantages in micromanipulation such as programmability, flexibility, versatility, high-throughput and ease of integration with other characterization systems, thus showing impressive performance compared to those of many other manipulation techniques. A lot of research on OET have been reported in recent years and the technology has developed rapidly in various fields of science and engineering. This work provides a comprehensive review of the OET technology, including its working mechanisms, experimental setups, applications in non-biological and biological scenarios, technology commercialization and future perspectives.
UR - http://www.scopus.com/inward/record.url?scp=85141736776&partnerID=8YFLogxK
U2 - 10.1039/d2cs00359g
DO - 10.1039/d2cs00359g
M3 - Review article
C2 - 36285556
AN - SCOPUS:85141736776
SN - 0306-0012
VL - 11
JO - Chemical Society Reviews
JF - Chemical Society Reviews
IS - 5
ER -