Nuclei classification using dual view CNNs with multi-crop module in histology images

Xiang Li, Wei Li*, Mengmeng Zhang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Histopathology image diagnostic technique is a quite common requirement; however, cell nuclei classification is still one of key challenge due to complex tissue structure and diversity of nuclear morphology. Cell nuclei categories are often defined by contextual information, including central nucleus and surrounding background. In this paper, we propose a Dual-View Convolutional Neural Networks (DV-CNNs) that captures contextual contents from different views. The DV-CNNs are composed of two independent pathways, one for global region and another for center local region. Noted that each pathway with “multi-crop module” can extract five different feature regions. Common networks do not fully utilize the local information, but the designed cropping module catches information for more complete features. In experiments, two pipelines are complementary to each other in score fusion. To verify the performance in proposed framework, it is evaluated on a colorectal adenocarcinoma image database with more than 20,000 nuclei. Compared with existing methods, our proposed DV-CNNs with multi-crop module demonstrate better performance.

Original languageEnglish
Title of host publicationPattern Recognition and Computer Vision - First Chinese Conference, PRCV 2018, Proceedings
EditorsCheng-Lin Liu, Tieniu Tan, Jie Zhou, Jian-Huang Lai, Xilin Chen, Nanning Zheng, Hongbin Zha
PublisherSpringer Verlag
Pages227-236
Number of pages10
ISBN (Print)9783030033347
DOIs
Publication statusPublished - 2018
Externally publishedYes
Event1st Chinese Conference on Pattern Recognition and Computer Vision, PRCV 2018 - Guangzhou, China
Duration: 23 Nov 201826 Nov 2018

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11257 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference1st Chinese Conference on Pattern Recognition and Computer Vision, PRCV 2018
Country/TerritoryChina
CityGuangzhou
Period23/11/1826/11/18

Keywords

  • Cell nuclei classification
  • Convolutional neural network
  • Histopathology image analysis

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