Novel prosthesis using silk fibroin for small caliber vascular

Xilan Ma, Chuanbao Cao*, Jinghua Li, Hesun Zhu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

A novel prosthesis using silk fibroin with blending heparin and sulfonated silk fibroin was studied. Anticoagulation activities of heparin/silk fibroin and sulfonated silk fibroin/silk fibroin vascular and mechanical property results showed that heparin/silk fibroin and sulfonated silk fibroin/silk fibroin vascular could meet the requirement of small caliber grafts. This study indicated that silk fibroin could be used for developing tissue engineering biological vascular grafts that could use for human coronary or low extremity artery bypasses.

Original languageEnglish
Pages (from-to)461-464
Number of pages4
JournalKey Engineering Materials
Volume288-289
DOIs
Publication statusPublished - 2005

Keywords

  • Anticoagulation
  • Heparin
  • Silk fibroin
  • Sulfonated silk fibroin

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