Mechanical properties and antithrombogenecity of blend membrane of silk fibroin

Yin Tang; Chuanbao Cao; Xilan Ma; Jinghua Li; Hesun Zhu

doi:10.4028/0-87849-967-9.445

Mechanical properties and antithrombogenecity of blend membrane of silk fibroin

Yin Tang, Chuanbao Cao^*, Xilan Ma, Jinghua Li, Hesun Zhu

^*Corresponding author for this work

School of Material Science and Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The silk fibroin blend membranes were prepared by adding a small amount of poly (vinyl alcohol) (PVA) and heparin. By controlling the preparation conditions, the tensile strength and elongation at break reached to 8.86 MPa and 231.8%, respectively. Meanwhile the in vitro antithrombogenecity significant increased. The clot times (APTT, TT and PT) all exceeded the measurement limit of clot detection instrument. It is expectable using these natural materials to prepare small caliber vessel.

Original language	English
Pages (from-to)	445-448
Number of pages	4
Journal	Key Engineering Materials
Volume	288-289
DOIs	https://doi.org/10.4028/0-87849-967-9.445
Publication status	Published - 2005

Keywords

Clot time
Heparin
Mechanical properties
Poly (vinyl alcohol)
Silk fibroin

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abstract = "The silk fibroin blend membranes were prepared by adding a small amount of poly (vinyl alcohol) (PVA) and heparin. By controlling the preparation conditions, the tensile strength and elongation at break reached to 8.86 MPa and 231.8%, respectively. Meanwhile the in vitro antithrombogenecity significant increased. The clot times (APTT, TT and PT) all exceeded the measurement limit of clot detection instrument. It is expectable using these natural materials to prepare small caliber vessel.",

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AU - Tang, Yin

AU - Cao, Chuanbao

AU - Ma, Xilan

AU - Li, Jinghua

AU - Zhu, Hesun

PY - 2005

Y1 - 2005

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AB - The silk fibroin blend membranes were prepared by adding a small amount of poly (vinyl alcohol) (PVA) and heparin. By controlling the preparation conditions, the tensile strength and elongation at break reached to 8.86 MPa and 231.8%, respectively. Meanwhile the in vitro antithrombogenecity significant increased. The clot times (APTT, TT and PT) all exceeded the measurement limit of clot detection instrument. It is expectable using these natural materials to prepare small caliber vessel.

KW - Clot time

KW - Heparin

KW - Mechanical properties

KW - Poly (vinyl alcohol)

KW - Silk fibroin

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VL - 288-289

SP - 445

EP - 448

JO - Key Engineering Materials

JF - Key Engineering Materials

ER -

Mechanical properties and antithrombogenecity of blend membrane of silk fibroin

Abstract

Keywords

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