Influence of Graft Density of Poly (N-Isopropylacrylamide)-Grafted Silica on Separation Performance

Yanli Liang; Zongjian Liu; Rongji Dai; Weiwei Meng; Yulin Deng

doi:10.1007/s10337-015-2966-z

Influence of Graft Density of Poly (N-Isopropylacrylamide)-Grafted Silica on Separation Performance

Yanli Liang, Zongjian Liu, Rongji Dai^*, Weiwei Meng, Yulin Deng

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Poly (N-isopropylacrylamide) (PNIPAAm)-grafted silica beads with variable graft densities were prepared by atom transfer radical polymerization (ATRP). The ATRP initiator on the surface of silica was prepared through the aminopropyl silica and 2-bromoisobutyryl bromide. Acetyl chloride was used to control the graft density. The content of carbon, hydrogen, and nitrogen were measured by elemental analyzer. The graft ratio was characterized by thermogravimetric analysis and the molecular weight of the polymer was determined by GPC analysis. The retention behavior of five steroids under different temperature was studied. Furthermore, the influence of temperature and graft densities to the separation of steroid compounds was investigated. The results indicated that graft density had a significant influence on the separation efficiency. Thinner PNIPAAm chains on hydrophilic silica surface can achieve the stationary phase with enhanced temperature sensitivity and better separation property.

Original language	English
Pages (from-to)	1349-1357
Number of pages	9
Journal	Chromatographia
Volume	78
Issue number	21-22
DOIs	https://doi.org/10.1007/s10337-015-2966-z
Publication status	Published - 29 Sept 2015

Keywords

ATRP
Graft densities
N-Isopropylacrylamide
Retention behavior

Access to Document

10.1007/s10337-015-2966-z

Cite this

@article{14147f5274c0485fb3cb021d23850e84,

title = "Influence of Graft Density of Poly (N-Isopropylacrylamide)-Grafted Silica on Separation Performance",

abstract = "Poly (N-isopropylacrylamide) (PNIPAAm)-grafted silica beads with variable graft densities were prepared by atom transfer radical polymerization (ATRP). The ATRP initiator on the surface of silica was prepared through the aminopropyl silica and 2-bromoisobutyryl bromide. Acetyl chloride was used to control the graft density. The content of carbon, hydrogen, and nitrogen were measured by elemental analyzer. The graft ratio was characterized by thermogravimetric analysis and the molecular weight of the polymer was determined by GPC analysis. The retention behavior of five steroids under different temperature was studied. Furthermore, the influence of temperature and graft densities to the separation of steroid compounds was investigated. The results indicated that graft density had a significant influence on the separation efficiency. Thinner PNIPAAm chains on hydrophilic silica surface can achieve the stationary phase with enhanced temperature sensitivity and better separation property.",

keywords = "ATRP, Graft densities, N-Isopropylacrylamide, Retention behavior",

author = "Yanli Liang and Zongjian Liu and Rongji Dai and Weiwei Meng and Yulin Deng",

note = "Publisher Copyright: {\textcopyright} 2015, Springer-Verlag Berlin Heidelberg.",

year = "2015",

month = sep,

day = "29",

doi = "10.1007/s10337-015-2966-z",

language = "English",

volume = "78",

pages = "1349--1357",

journal = "Chromatographia",

issn = "0009-5893",

publisher = "Springer",

number = "21-22",

}

TY - JOUR

T1 - Influence of Graft Density of Poly (N-Isopropylacrylamide)-Grafted Silica on Separation Performance

AU - Liang, Yanli

AU - Liu, Zongjian

AU - Dai, Rongji

AU - Meng, Weiwei

AU - Deng, Yulin

PY - 2015/9/29

Y1 - 2015/9/29

N2 - Poly (N-isopropylacrylamide) (PNIPAAm)-grafted silica beads with variable graft densities were prepared by atom transfer radical polymerization (ATRP). The ATRP initiator on the surface of silica was prepared through the aminopropyl silica and 2-bromoisobutyryl bromide. Acetyl chloride was used to control the graft density. The content of carbon, hydrogen, and nitrogen were measured by elemental analyzer. The graft ratio was characterized by thermogravimetric analysis and the molecular weight of the polymer was determined by GPC analysis. The retention behavior of five steroids under different temperature was studied. Furthermore, the influence of temperature and graft densities to the separation of steroid compounds was investigated. The results indicated that graft density had a significant influence on the separation efficiency. Thinner PNIPAAm chains on hydrophilic silica surface can achieve the stationary phase with enhanced temperature sensitivity and better separation property.

AB - Poly (N-isopropylacrylamide) (PNIPAAm)-grafted silica beads with variable graft densities were prepared by atom transfer radical polymerization (ATRP). The ATRP initiator on the surface of silica was prepared through the aminopropyl silica and 2-bromoisobutyryl bromide. Acetyl chloride was used to control the graft density. The content of carbon, hydrogen, and nitrogen were measured by elemental analyzer. The graft ratio was characterized by thermogravimetric analysis and the molecular weight of the polymer was determined by GPC analysis. The retention behavior of five steroids under different temperature was studied. Furthermore, the influence of temperature and graft densities to the separation of steroid compounds was investigated. The results indicated that graft density had a significant influence on the separation efficiency. Thinner PNIPAAm chains on hydrophilic silica surface can achieve the stationary phase with enhanced temperature sensitivity and better separation property.

KW - ATRP

KW - Graft densities

KW - N-Isopropylacrylamide

KW - Retention behavior

UR - http://www.scopus.com/inward/record.url?scp=84945469435&partnerID=8YFLogxK

U2 - 10.1007/s10337-015-2966-z

DO - 10.1007/s10337-015-2966-z

M3 - Article

AN - SCOPUS:84945469435

SN - 0009-5893

VL - 78

SP - 1349

EP - 1357

JO - Chromatographia

JF - Chromatographia

IS - 21-22

ER -

Influence of Graft Density of Poly (N-Isopropylacrylamide)-Grafted Silica on Separation Performance

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this