Increasing diversity in connectomics with the Chinese Human Connectome Project

Jianqiao Ge, Guoyuan Yang, Meizhen Han, Sizhong Zhou, Weiwei Men, Lang Qin, Bingjiang Lyu, Hai Li, Haobo Wang, Hengyi Rao, Zaixu Cui, Hesheng Liu, Xi Nian Zuo, Jia Hong Gao*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Cultural differences and biological diversity play important roles in shaping human brain structure and function. To date, most large-scale multimodal neuroimaging datasets have been obtained primarily from people living in Western countries, omitting the crucial contrast with populations living in other regions. The Chinese Human Connectome Project (CHCP) aims to address these resource and knowledge gaps by acquiring imaging, genetic and behavioral data from a large sample of participants living in an Eastern culture. The CHCP collected multimodal neuroimaging data from healthy Chinese adults using a protocol comparable to that of the Human Connectome Project. Comparisons between the CHCP and Human Connectome Project revealed both commonalities and distinctions in brain structure, function and connectivity. The corresponding large-scale brain parcellations were highly reproducible across the two datasets, with the language processing task showing the largest differences. The CHCP dataset is publicly available in an effort to facilitate transcultural and cross-ethnic brain–mind studies.

Original languageEnglish
Pages (from-to)163-172
Number of pages10
JournalNature Neuroscience
Volume26
Issue number1
DOIs
Publication statusPublished - Jan 2023

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