Heterogeneous Integration of Thin-Film Organic and Inorganic Devices for Optical Based Bioelectrical and Chemical Sensing

He Ding*, Yanxiu Peng, Guoqing Lv, Yang Xie, Junyu Chen, Zhao Shi, Yuping Deng, Lan Yin, Jian Yang, Yongtian Wang, Xing Sheng*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Directly visualizing electrical and chemical signals via optical approaches is an effective and powerful method for analyzing biological activities in a remote and high-throughput manner. Here we develop a heterogeneously integrated optoelectronic sensor that optically monitors the changes of bioelectrical and biochemical signals. Fabricated via epitaxial liftoff and transfer printing, the thin-film, microscale sensor combines a photodiode and a light-emitting diode (LED) made of inorganic III-V compound semiconductor heterostructures, as well as an organic electrochemical transistor (OECT). Ascribed to the matching condition among the heterogeneously integrated components, luminescent emissions of the sensor, which can be captured with a fluorescence microscope, dynamically respond to input electrical signals and are systematically characterized. Through voltage dependent luminance variations, the device optically records synthesized electrocardiography (ECG) signals with peak amplitudes from 100 mV to 10 mV. Furthermore, the integrated sensor is capable of selectively detecting calcium variations when immersing into the aqueous solution. The integrated sensor combines the advantages of inorganic and organic semiconductors and offers opportunities to wirelessly detect biological activities at a large scale.

Original languageEnglish
Article number5200107
JournalIEEE Journal of Selected Topics in Quantum Electronics
Volume29
Issue number3
DOIs
Publication statusPublished - 2023

Keywords

  • Biological sensors
  • heterogeneous integration
  • optoelectronics
  • transfer printing

Fingerprint

Dive into the research topics of 'Heterogeneous Integration of Thin-Film Organic and Inorganic Devices for Optical Based Bioelectrical and Chemical Sensing'. Together they form a unique fingerprint.

Cite this