Glucose dispersion measurement using white-light LCI

J. Liu; M. Bagherzadeh; C. K. Hitzenberger; M. Pircher; R. J. Zawadzki; A. F. Fercher

doi:10.1117/12.478974

Glucose dispersion measurement using white-light LCI

J. Liu^*, M. Bagherzadeh, C. K. Hitzenberger, M. Pircher, R. J. Zawadzki, A. F. Fercher

^*Corresponding author for this work

Research output: Contribution to journal › Conference article › peer-review

6 Citations (Scopus)

Abstract

We measured second order dispersion of glucose solution using a Michelson Low Coherent Interferometer (LCI). Three different glucose concentrations: 20mg/dl (hypoglycemia), l00mg/dl (normal level), and 500mg/dl (hyperglycemia) are investigated over the wavelength range O.5μm to 0.85μm, and the investigation shows that different concentrations are associated with different second-order dispersions. The second-order dispersions for wavelengths from 0.55μm to 0.8μm are determined by Fourier analysis of the interferogram. This approach can be applied to measure the second-order dispersion for distinguishing the different glucose concentrations. It can be considered as a potentially noninvasive method to determine glucose concentration in human eye. A brief discussion is presented in this poster as well.

Original language	English
Pages (from-to)	348-351
Number of pages	4
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	4956
DOIs	https://doi.org/10.1117/12.478974
Publication status	Published - 2003
Externally published	Yes
Event	PROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII - San Jose, CA, United States Duration: 27 Jan 2003 → 29 Jan 2003

Keywords

Coherence and statistical optics
Dispersion
Interferometry
Optical properties
Thermal light sources

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10.1117/12.478974

Cite this

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title = "Glucose dispersion measurement using white-light LCI",

abstract = "We measured second order dispersion of glucose solution using a Michelson Low Coherent Interferometer (LCI). Three different glucose concentrations: 20mg/dl (hypoglycemia), l00mg/dl (normal level), and 500mg/dl (hyperglycemia) are investigated over the wavelength range O.5μm to 0.85μm, and the investigation shows that different concentrations are associated with different second-order dispersions. The second-order dispersions for wavelengths from 0.55μm to 0.8μm are determined by Fourier analysis of the interferogram. This approach can be applied to measure the second-order dispersion for distinguishing the different glucose concentrations. It can be considered as a potentially noninvasive method to determine glucose concentration in human eye. A brief discussion is presented in this poster as well.",

keywords = "Coherence and statistical optics, Dispersion, Interferometry, Optical properties, Thermal light sources",

author = "J. Liu and M. Bagherzadeh and Hitzenberger, {C. K.} and M. Pircher and Zawadzki, {R. J.} and Fercher, {A. F.}",

year = "2003",

doi = "10.1117/12.478974",

language = "English",

volume = "4956",

pages = "348--351",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "PROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII ; Conference date: 27-01-2003 Through 29-01-2003",

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TY - JOUR

T1 - Glucose dispersion measurement using white-light LCI

AU - Liu, J.

AU - Bagherzadeh, M.

AU - Hitzenberger, C. K.

AU - Pircher, M.

AU - Zawadzki, R. J.

AU - Fercher, A. F.

PY - 2003

Y1 - 2003

N2 - We measured second order dispersion of glucose solution using a Michelson Low Coherent Interferometer (LCI). Three different glucose concentrations: 20mg/dl (hypoglycemia), l00mg/dl (normal level), and 500mg/dl (hyperglycemia) are investigated over the wavelength range O.5μm to 0.85μm, and the investigation shows that different concentrations are associated with different second-order dispersions. The second-order dispersions for wavelengths from 0.55μm to 0.8μm are determined by Fourier analysis of the interferogram. This approach can be applied to measure the second-order dispersion for distinguishing the different glucose concentrations. It can be considered as a potentially noninvasive method to determine glucose concentration in human eye. A brief discussion is presented in this poster as well.

AB - We measured second order dispersion of glucose solution using a Michelson Low Coherent Interferometer (LCI). Three different glucose concentrations: 20mg/dl (hypoglycemia), l00mg/dl (normal level), and 500mg/dl (hyperglycemia) are investigated over the wavelength range O.5μm to 0.85μm, and the investigation shows that different concentrations are associated with different second-order dispersions. The second-order dispersions for wavelengths from 0.55μm to 0.8μm are determined by Fourier analysis of the interferogram. This approach can be applied to measure the second-order dispersion for distinguishing the different glucose concentrations. It can be considered as a potentially noninvasive method to determine glucose concentration in human eye. A brief discussion is presented in this poster as well.

KW - Coherence and statistical optics

KW - Dispersion

KW - Interferometry

KW - Optical properties

KW - Thermal light sources

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DO - 10.1117/12.478974

M3 - Conference article

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EP - 351

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - PROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII

Y2 - 27 January 2003 through 29 January 2003

ER -

Glucose dispersion measurement using white-light LCI

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Keywords

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