Freehand OCT with real-time lateral motion tracking

Xuan Liu, Yong Huang, Peter Gehlbach, Jin U. Kang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Freehand optical coherence tomography (OCT) systems without mechanical scanners can offer greater freedom to access and image sites of interest. However, the scanning velocity during freehand scan is irregular; therefore pseudo B-scan images obtained by stacking sequentially acquired A-scans have a non-uniform spatial sampling rate in the lateral dimension. In this study, we developed a speckle decorrelation method to estimate lateral displacement between sequentially acquired A-scans and used the information extracted from speckle analysis to correct the time-varying lateral scanning speed. We applied this method to a handheld OCT probe and performed calibration experiments to validate our model. Furthermore we demonstrated distortion-free, freehand OCT imaging of various samples including human tissue, in vivo.

Original languageEnglish
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
DOIs
Publication statusPublished - 2013
Externally publishedYes
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII - San Francisco, CA, United States
Duration: 4 Feb 20136 Feb 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8571
ISSN (Print)1605-7422

Conference

ConferenceOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
Country/TerritoryUnited States
CitySan Francisco, CA
Period4/02/136/02/13

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Liu, X., Huang, Y., Gehlbach, P., & Kang, J. U. (2013). Freehand OCT with real-time lateral motion tracking. In Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII Article 85711P (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8571). https://doi.org/10.1117/12.2006973