@inproceedings{20159008c50a4ab58ce1cf7d7dca4037,
title = "Determination of singlet oxygen quantum yield of HiPorfin using Singlet Oxygen Sensor Green",
abstract = "Singlet oxygen (1O2) is widely considered to be the predominant cytotoxic agent for photodynamic therapy (PDT), and the 1O2 quantum yield is a key characteristic for the newly developed photosensitizers. In this study, 1O2 generation from the HiPorfin is monitored indirectly by using the fluorescence probe Singlet Oxygen Sensor Green (SOSG). The good linear relationship between the concentration of HiPorfin and the initial reaction rate of SOSG is observed, and the 1O2 quantum yield of HiPorfin is determined to be 0.124 ± 0.001, as compared to the standard reference of Rose Bengal. The results suggest that SOSG can be useful for 1O2 quantum yield determination for the potential photosensitizers in PDT.",
keywords = "Fluorescence, HiPorfin, Initial reaction rate, Photodynamic therapy, Quantum yield, Singlet Oxygen Sensor Green, Singlet oxygen",
author = "Huiyun Lin and Yi Shen and Defu Chen and Lisheng Lin and Buhong Li and Shusen Xie",
year = "2010",
doi = "10.1117/12.870108",
language = "English",
isbn = "9780819483751",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Optics in Health Care and Biomedical Optics IV",
note = "Optics in Health Care and Biomedical Optics IV ; Conference date: 18-10-2010 Through 20-10-2010",
}