Asymptotic behavior of solutions to a tumor angiogenesis model with chemotaxis-haptotaxis

Peter Y.H. Pang, Yifu Wang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

This paper studies the following system of differential equations modeling tumor angiogenesis in a bounded smooth domain Ω ⊂ ℝN (N = 1, 2): (Equation presented) where α, ρ, λ, μ and γ are positive parameters. For any reasonably regular initial data (p0, c0, w0), we prove the global boundedness (L-norm) of p via an iterative method. Furthermore, we investigate the long-time behavior of solutions to the above system under an additional mild condition, and improve previously known results. In particular, in the one-dimensional case, we show that the solution (p, c,w) converges to (1, 0, 1) with an explicit exponential rate as time tends to infinity.

Original languageEnglish
Pages (from-to)1387-1412
Number of pages26
JournalMathematical Models and Methods in Applied Sciences
Volume29
Issue number7
DOIs
Publication statusPublished - 30 Jun 2019

Keywords

  • Angiogenesis
  • asymptotic behavior
  • boundedness
  • chemotaxis
  • haptotaxis

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