@inproceedings{f2a9418bdcf94cd4b282f97ddb709036,
title = "An isothermal nanocalorimetric platform for antimicrobial susceptibility testing based on bacterial metabolic heat measurements",
abstract = "We present an optimized isothermal nanocalorimetric platform comprising thermopile sensors for performing highly sensitive and rapid bacterial metabolic heat measurements. Based on the specific evolution of the bacterial heat flow curves, different metabolic states could be identified and the metabolic heat generation under various conditions, such as different culture media and temperatures, was studied. We demonstrated the feasibility of fast antimicrobial susceptibility testing and the possibility to determine minimum inhibitor concentrations within a few hours, i.e. on a much shorter timescale than with current clinical setting.",
keywords = "Antimicrobial susceptibility, Bacteria, Metabolic heat, Nanocalorimetry",
author = "Yang Liu and Thomas Lehnert and Gijs, {Martin A.M.}",
note = "Publisher Copyright: Copyright {\textcopyright} (2018) by Chemical and Biological Microsystems Society. All rights reserved.; 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 ; Conference date: 11-11-2018 Through 15-11-2018",
year = "2018",
language = "English",
series = "22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018",
publisher = "Chemical and Biological Microsystems Society",
pages = "717--719",
booktitle = "22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018",
}