Aerobic oxidative C-H phosphorylation of quinoxalines under catalyst-free conditions

Qiaoyu Gan; Haibo Liu; Zeqi Jiang; Junmei Xia; Zhenhua Gao; Yongbiao Guo; Hongliang Wen

doi:10.1039/d3cc02848h

Aerobic oxidative C-H phosphorylation of quinoxalines under catalyst-free conditions

Qiaoyu Gan, Haibo Liu, Zeqi Jiang, Junmei Xia, Zhenhua Gao^*, Yongbiao Guo^*, Hongliang Wen^*

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

We herein report a direct and efficient protocol for phosphorylation of quinoxalines, which employs aerobic oxygen as the green oxidant under catalyst-free conditions. This methodology represents one of the most environmentally friendly and easily handled protocols, providing a series of phosphorylated quinoxalines in good to excellent yields. Control experiments clearly indicated that the reaction followed a dearomatization-rearomatization strategy.

Original language	English
Pages (from-to)	11089-11092
Number of pages	4
Journal	Chemical Communications
Volume	59
Issue number	74
DOIs	https://doi.org/10.1039/d3cc02848h
Publication status	Published - 21 Aug 2023

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10.1039/d3cc02848h

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abstract = "We herein report a direct and efficient protocol for phosphorylation of quinoxalines, which employs aerobic oxygen as the green oxidant under catalyst-free conditions. This methodology represents one of the most environmentally friendly and easily handled protocols, providing a series of phosphorylated quinoxalines in good to excellent yields. Control experiments clearly indicated that the reaction followed a dearomatization-rearomatization strategy.",

author = "Qiaoyu Gan and Haibo Liu and Zeqi Jiang and Junmei Xia and Zhenhua Gao and Yongbiao Guo and Hongliang Wen",

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T1 - Aerobic oxidative C-H phosphorylation of quinoxalines under catalyst-free conditions

AU - Gan, Qiaoyu

AU - Liu, Haibo

AU - Jiang, Zeqi

AU - Xia, Junmei

AU - Gao, Zhenhua

AU - Guo, Yongbiao

AU - Wen, Hongliang

PY - 2023/8/21

Y1 - 2023/8/21

N2 - We herein report a direct and efficient protocol for phosphorylation of quinoxalines, which employs aerobic oxygen as the green oxidant under catalyst-free conditions. This methodology represents one of the most environmentally friendly and easily handled protocols, providing a series of phosphorylated quinoxalines in good to excellent yields. Control experiments clearly indicated that the reaction followed a dearomatization-rearomatization strategy.

AB - We herein report a direct and efficient protocol for phosphorylation of quinoxalines, which employs aerobic oxygen as the green oxidant under catalyst-free conditions. This methodology represents one of the most environmentally friendly and easily handled protocols, providing a series of phosphorylated quinoxalines in good to excellent yields. Control experiments clearly indicated that the reaction followed a dearomatization-rearomatization strategy.

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U2 - 10.1039/d3cc02848h

DO - 10.1039/d3cc02848h

M3 - Article

C2 - 37642316

AN - SCOPUS:85170264797

SN - 1359-7345

VL - 59

SP - 11089

EP - 11092

JO - Chemical Communications

JF - Chemical Communications

IS - 74

ER -

Aerobic oxidative C-H phosphorylation of quinoxalines under catalyst-free conditions

Abstract

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