Abstract
A novel cross-linking reagent, methoxypolyethelene glycol-glutamic acid, was synthesized and used to modify bovine hemoglobin. Bis-tetrameric hemoglobin with moderate affinity for O2 was obtained under the controlled reaction conditions.
Original language | English |
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Pages (from-to) | 327-330 |
Number of pages | 4 |
Journal | Biotechnology Letters |
Volume | 25 |
Issue number | 4 |
DOIs | |
Publication status | Published - Feb 2003 |
Externally published | Yes |
Keywords
- Bovine hemoglobin
- Cross-linking reagent
- Modification
- Polyethylene glycol