温敏型分子印迹量子点生物传感器用于检测牛血红蛋白

Ai Qin Luo; Hong Yang Liu; Xin Zhang; Wei Jie Chen; Yuan Yuan Li; Li Quan Sun

doi:10.15918/j.tbit1001-0645.2019.059

温敏型分子印迹量子点生物传感器用于检测牛血红蛋白

Translated title of the contribution: Thermosensitive Molecularly Imprinted Quantum Dots as Biosensor for the Detection of Bovine Hemoglobin

Ai Qin Luo, Hong Yang Liu, Xin Zhang, Wei Jie Chen, Yuan Yuan Li, Li Quan Sun

School of Life Science

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

A thermosensitive biosensor based on molecularly imprinted quantum dots (QD@MIPs) was developed and used for rapid detection of bovine hemoglobin (BHb). The experimental results show that, the prepared QD@MIPs can provide a fast fluorescence response to BHb and achieve the adsorption equilibrium in 15 min. Under optimal conditions, the fluorescence quenching of BHb is proportional to the concentration in the range of 0.15~2.3 μmol/L with a correlation coefficient of 0.986 9, and the detection limit is 0.097 μmol/L. Moreover, the prepared QD@MIPs possesses thermosensitive, this feature can endow it rapid adsorption and release of template protein by changing the temperature in bio-analysis.

Translated title of the contribution	Thermosensitive Molecularly Imprinted Quantum Dots as Biosensor for the Detection of Bovine Hemoglobin
Original language	Chinese (Traditional)
Pages (from-to)	667-673
Number of pages	7
Journal	Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology
Volume	40
Issue number	6
DOIs	https://doi.org/10.15918/j.tbit1001-0645.2019.059
Publication status	Published - 1 Jun 2020

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title = "温敏型分子印迹量子点生物传感器用于检测牛血红蛋白",

abstract = "A thermosensitive biosensor based on molecularly imprinted quantum dots (QD@MIPs) was developed and used for rapid detection of bovine hemoglobin (BHb). The experimental results show that, the prepared QD@MIPs can provide a fast fluorescence response to BHb and achieve the adsorption equilibrium in 15 min. Under optimal conditions, the fluorescence quenching of BHb is proportional to the concentration in the range of 0.15~2.3 μmol/L with a correlation coefficient of 0.986 9, and the detection limit is 0.097 μmol/L. Moreover, the prepared QD@MIPs possesses thermosensitive, this feature can endow it rapid adsorption and release of template protein by changing the temperature in bio-analysis.",

keywords = "Biosensor, Molecularly imprinting, Proteins detection, Thermosensitivity",

author = "Luo, {Ai Qin} and Liu, {Hong Yang} and Xin Zhang and Chen, {Wei Jie} and Li, {Yuan Yuan} and Sun, {Li Quan}",

year = "2020",

month = jun,

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doi = "10.15918/j.tbit1001-0645.2019.059",

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T1 - 温敏型分子印迹量子点生物传感器用于检测牛血红蛋白

AU - Luo, Ai Qin

AU - Liu, Hong Yang

AU - Zhang, Xin

AU - Chen, Wei Jie

AU - Li, Yuan Yuan

AU - Sun, Li Quan

PY - 2020/6/1

Y1 - 2020/6/1

N2 - A thermosensitive biosensor based on molecularly imprinted quantum dots (QD@MIPs) was developed and used for rapid detection of bovine hemoglobin (BHb). The experimental results show that, the prepared QD@MIPs can provide a fast fluorescence response to BHb and achieve the adsorption equilibrium in 15 min. Under optimal conditions, the fluorescence quenching of BHb is proportional to the concentration in the range of 0.15~2.3 μmol/L with a correlation coefficient of 0.986 9, and the detection limit is 0.097 μmol/L. Moreover, the prepared QD@MIPs possesses thermosensitive, this feature can endow it rapid adsorption and release of template protein by changing the temperature in bio-analysis.

AB - A thermosensitive biosensor based on molecularly imprinted quantum dots (QD@MIPs) was developed and used for rapid detection of bovine hemoglobin (BHb). The experimental results show that, the prepared QD@MIPs can provide a fast fluorescence response to BHb and achieve the adsorption equilibrium in 15 min. Under optimal conditions, the fluorescence quenching of BHb is proportional to the concentration in the range of 0.15~2.3 μmol/L with a correlation coefficient of 0.986 9, and the detection limit is 0.097 μmol/L. Moreover, the prepared QD@MIPs possesses thermosensitive, this feature can endow it rapid adsorption and release of template protein by changing the temperature in bio-analysis.

KW - Biosensor

KW - Molecularly imprinting

KW - Proteins detection

KW - Thermosensitivity

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ER -

温敏型分子印迹量子点生物传感器用于检测牛血红蛋白

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