He is mainly engaged in the research of synthetic biology, microbiome and microecology. The main research content is the rational design of the microbial synthesis pathway of plant natural products, the construction of mathematical models of plant endophyte community and the study of metabolic interaction mechanism. The stoichiometric network analysis technology of biological reaction system is used to predict microbial interaction and the interaction of artificial pathway and metabolic network of chassis cells. Then, combining omics technology and molecular biology technology, industrial microorganisms or microbial flora can be obtained to meet the application needs.

2005.09-2009.07 Shandong University, majoring in Microbial Technology, Bachelor degree
2009.09-2013.04 PhD in Biosystems Engineering, University of Minnesota, USA (Supervisor: Roger R. Ruan)

2013.07-2015.12 Postdoctoral Fellow, School of Engineering, Peking University (Co-supervisor: Xiaolei Wu)
2016.01-2019.02 Assistant Researcher of Professor Wu Xiaolei's Research Group, School of Engineering, Peking University
2019.03-Present Assistant Professor, School of Chemistry and Chemical Engineering, Beijing Institute of Technology

Major research projects undertaken and organized
XXXXXXXXXXXXXXXXXXXXXXXXXX, military science and XX project, XXX - XXX - XXX - XXX - XXX - XXX, head of ($2 million, 2022.3-2023.12) < br > 2. Development and application of global dynamic coupling algorithm for cell growth and heterologous production, National Natural Science Foundation of China, 221708024, Person in charge (600,000, 2022.1-2025.12)
3. Digital Cell Modeling and artificial Simulation, National Key R & D Program "Synthetic Biology" key project, 2020YFA0908300, research backbone (600,000, 2020.10-2025.10)
4. Mechanism of action of endophytic flora regulating the synthesis of triterpenoids from Licorice and development of bacteriological agents, State Key Laboratory of Biochemical Engineering, Chinese Academy of Sciences, Open Foundation Project, 2020KF-05, Director (150,000, 2020.01-2022.12)
5. Microbiology of Interinteracting Fatty acid Degradation in Biogas Production Process and response mechanism to environmental Stress, Intergovernmental Key Project for International Science and Technology Innovation Cooperation, 2016YFE0127700, Sub-project leader (446,400, 2017.01-2019.12)
6. Building Cooperative microbial flora using metabolic network Model to Improve the efficiency of microbial oil pollution control, Research Project of China Petroleum Science and Technology Innovation Foundation, 2016D-5007-0701, Director (180,000, 2016.10-2018.10)
7. Study on the mechanism of microbial synergistic utilization of petroleum hydrocarbons, Youth Science Foundation of National Natural Foundation of China, 31400112, Director (200000, 2015.01-2016.12)
Academic Papers
1. Hu B#, Das P#, Lv X#, Shi M, Aa J, Wang K, Duan L, Gilbert JA, Nie Y, Wu X*. (2022) Effects of ‘healthy’ fecal microbiota transplantation against the deterioration of depression in Fawn-hooded rats. mSystems. 7(3): e0021822. (IF=7.328)
2. Hu B#, Zhao J#, Nie Y*, Qin X, Zhang K, Xing J, Wu X*. (2021) Bioemulsification and microbial community reconstruction in thermally processed crude oil. Microorganisms. 9(10): 2054. (IF=4.926)
3. Yachao Chen, Nannan Li, ZIDI Liu, Bing Hu, Chun Li. (2021) Metagenomic mining of functional genes related to glycyrrhizic acid synthesis from endophytic bacteria licorice. Chinese Journal of Bioengineering. 41(9): 37-47. (br>) 4. Zhao J#, Hu B#, Dolfing J, Li Y, Tang Y, Jiang Y, Chi C, Xing J, Nie Y*, Wu X*. (2021) Thermodynamically favorable reactions shape the archaeal community affecting bacterial community assembly in oil reservoirs. Sci Total Environ. 781:146506. (IF=10.754)
5. Chen Y, Hu B*, Xing J, Li C*. (2021) Endophytes: the novel sources for plant terpenoid biosynthesis. Appl Microbiol Biotechnol. 105(11): 451-4513. (IF=5.560)
6. Hu B, Wang M, Geng S, Wen L, Wu M, Nie Y, Tang Y, Wu X*. (2020) Metabolic exchange with alkane non-consumer Pseudomonas stutzeri SLG510A3-8 improves the n-alkane biodegradation of the alkane degrader Dietzia sp. DQ12-45-1b. Appl Environ Microbiol. 86(8): e02931-19. (IF=5.005)
7. Hu B, Nie Y, Geng S, Wu X*. (2015) Complete genome sequence of the petroleum-emulsifying bacterium Pseudomonas stutzeri SLG510A3-8. J Biotechnol.211:1-2. (IF=3.595)
8. Hu B, Yang Q, Cai M, Tang Y, Zhao G, Wu X*. (2015) Negadavirga Shengliensis gen. nov., sp. nov., a novel member of the family Cyclobacteriaceae isolated from oil-contaminated saline soil. Antonie van Leeuw J Microb. 107:663-73. (IF=2.158)
9. Hu B, Zhou W, Min M, Du Z, Chen P, Ma X, Liu Y, Lei H, Shi J, Ruan R*. (2013) Development of an effective acidogenically digested swine manure-based algal system for improved wastewater treatment and biofuel and feed production. Appl Energ. 107: 255-63. (IF=11.446)
10. Hu B, Min M, Zhou W, Du Z, Mohr M, Chen P, Zhu J, Cheng Y, Liu Y, Ruan R*. (2012) Enhanced mixotrophic growth of microalga Chlorella sp. on pretreated swine manure for simultaneous biofuel feedstock production and nutrient removal. Bioresour Technol. 126:71-9. (IF=11.889)
11. Hu B, Min M, Zhou W, Li Y, Mohr M, Cheng Y, Lei H, Liu Y, Liu X, Chen P, Ruan R*. (2012) Influence of exogenous CO2 on biomass and lipid accumulation of microalgae Auxenochlorella protothecoides cultivated in concentrated municipal wastewater. Appl Biochem Biotechnol. 166:1661-73. (IF=3.094)
Patent
1. Wu Xiaolei; Hu Bing; Nie Yong; Wu Mengdi; A method and product for improving the ability of other microorganisms by using metabolites of specific microorganisms, China Patent for Invention, 2019-08-26, Application number: 201910788970.5.
2. Hu Bing; Li Chun; Liu Zidi; Li Nannan; A bioinformatic method for the rational screening of endophytic bacteria that can promote the accumulation of active products in Urallicorice root, China Invention Patent, 2022-01-10, Application number: 202210020900.7.
Awards
2020 International Genetic Engineering Machine Competition (iGEM) Team Silver Award
Beijing Institute of Technology Admission Contribution Award in 2020
2021 Annual Assessment of Outstanding Personnel of School of Chemistry and Chemical Engineering, Beijing Institute of Technology
2021 National Science Popularization Day Outstanding Activity Award