Visible-Light-Induced Trifluoromethylation of Allylic Alcohols

Bowen Li; Wubing Zeng; Lin Wang; Zhishuai Geng; Teck Peng Loh; Peizhong Xie

doi:10.1021/acs.orglett.1c01767

Visible-Light-Induced Trifluoromethylation of Allylic Alcohols

Bowen Li, Wubing Zeng, Lin Wang, Zhishuai Geng, Teck Peng Loh^*, Peizhong Xie^*

^*此作品的通讯作者

材料学院

科研成果: 期刊稿件 › 文章 › 同行评审

19 引用（Scopus）

摘要

An organic photoredox-catalyzed dehydroxylative trifluoromethylation of allylic alcohols was developed in an environmentally benign manner. In this reaction, the readily available CF3SO2Na was selected as the trifluoromethylation reagent. The in situ generated byproduct SO2 was reutilized to activate C-OH bond, which enabled this dehydroxylative trifluoromethylation to be performed conveniently. A variety of multifunctionalized CF3-allylic compounds were obtained in high yields and excellent stereoselectivity.

源语言	英语
页（从-至）	5235-5240
页数	6
期刊	Organic Letters
卷	23
期	13
DOI	https://doi.org/10.1021/acs.orglett.1c01767
出版状态	已出版 - 2 7月 2021

访问文件

10.1021/acs.orglett.1c01767

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{6a49bf2e810240dd909dfbb99a17df98,

title = "Visible-Light-Induced Trifluoromethylation of Allylic Alcohols",

abstract = "An organic photoredox-catalyzed dehydroxylative trifluoromethylation of allylic alcohols was developed in an environmentally benign manner. In this reaction, the readily available CF3SO2Na was selected as the trifluoromethylation reagent. The in situ generated byproduct SO2 was reutilized to activate C-OH bond, which enabled this dehydroxylative trifluoromethylation to be performed conveniently. A variety of multifunctionalized CF3-allylic compounds were obtained in high yields and excellent stereoselectivity.",

author = "Bowen Li and Wubing Zeng and Lin Wang and Zhishuai Geng and Loh, {Teck Peng} and Peizhong Xie",

note = "Publisher Copyright: {\textcopyright} 2021 American Chemical Society.",

year = "2021",

month = jul,

day = "2",

doi = "10.1021/acs.orglett.1c01767",

language = "English",

volume = "23",

pages = "5235--5240",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "13",

}

TY - JOUR

T1 - Visible-Light-Induced Trifluoromethylation of Allylic Alcohols

AU - Li, Bowen

AU - Zeng, Wubing

AU - Wang, Lin

AU - Geng, Zhishuai

AU - Loh, Teck Peng

AU - Xie, Peizhong

PY - 2021/7/2

Y1 - 2021/7/2

N2 - An organic photoredox-catalyzed dehydroxylative trifluoromethylation of allylic alcohols was developed in an environmentally benign manner. In this reaction, the readily available CF3SO2Na was selected as the trifluoromethylation reagent. The in situ generated byproduct SO2 was reutilized to activate C-OH bond, which enabled this dehydroxylative trifluoromethylation to be performed conveniently. A variety of multifunctionalized CF3-allylic compounds were obtained in high yields and excellent stereoselectivity.

AB - An organic photoredox-catalyzed dehydroxylative trifluoromethylation of allylic alcohols was developed in an environmentally benign manner. In this reaction, the readily available CF3SO2Na was selected as the trifluoromethylation reagent. The in situ generated byproduct SO2 was reutilized to activate C-OH bond, which enabled this dehydroxylative trifluoromethylation to be performed conveniently. A variety of multifunctionalized CF3-allylic compounds were obtained in high yields and excellent stereoselectivity.

UR - http://www.scopus.com/inward/record.url?scp=85110301148&partnerID=8YFLogxK

U2 - 10.1021/acs.orglett.1c01767

DO - 10.1021/acs.orglett.1c01767

M3 - Article

C2 - 34156254

AN - SCOPUS:85110301148

SN - 1523-7060

VL - 23

SP - 5235

EP - 5240

JO - Organic Letters

JF - Organic Letters

IS - 13

ER -

Visible-Light-Induced Trifluoromethylation of Allylic Alcohols

摘要

访问文件

其它文件与链接

指纹

引用此