摘要
A gold-catalyzed three-component coupling reaction (A3 reaction) was developed as an efficient approach for the synthesis of challenging 2, 4-disubstituted quinoline derivatives. Compared to previously reported Cu/Au bi-catalyst system, this protocol enables achieving A3 reaction only in the presence of triazole-gold catalyst. Notably, 4-alkyl substituted or 2-alkyl substituted quinoline derivatives were obtained with good yields, which highlighted the unique advantage of this new strategy.
源语言 | 英语 |
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页(从-至) | 392-394 |
页数 | 3 |
期刊 | Chinese Chemical Letters |
卷 | 30 |
期 | 2 |
DOI | |
出版状态 | 已出版 - 2月 2019 |
已对外发布 | 是 |