摘要
High performance liquid chromatography (HPLC) has been widely used in the quantitative analysis of erythromycin 9-oxime, an important intermediate for the synthesis of new erythromycin derivatives. HPLC method is used to analyse the content of erythromycin 9-oxime, and the stability of the method is evaluated. The results show that this method has a good stability and high accuracy. External method is applied, with the following chromatographic conditions: description of column: Nova-pak C18, eluent used: V(CH 3CN): V (0.033 mol/L KH2PO4) = (30: 70), detection wavelength; 205 nm, detection sensitity 0.1AUFS.
源语言 | 英语 |
---|---|
页(从-至) | 771-773 |
页数 | 3 |
期刊 | He Jishu/Nuclear Techniques |
卷 | 22 |
期 | 6 |
出版状态 | 已出版 - 1999 |
指纹
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Wang, J. Y., Luo, A. Q., Deng, Y. L., Gu, J. L., & Ma, W. (1999). The HPLC analysis of erythromycin 9-oxime. He Jishu/Nuclear Techniques, 22(6), 771-773.