摘要
A series of five new fluoro-substituted aroylhydrazones were prepared and structurally characterized by elemental analysis, IR, UV-Vis and 1H NMR spectroscopy, as well as single crystal X-ray diffraction. The compounds were evaluated for their antibacterial (Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Pseudomonas fluorescence) and antifungal (Candida albicans and Aspergillus niger) activities by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) method. The biological assay indicated that the presence of the electron-withdrawing groups in the aroylhydrazones improved their antimicrobial activities.
源语言 | 英语 |
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页(从-至) | 541-547 |
页数 | 7 |
期刊 | Acta Chimica Slovenica |
卷 | 63 |
期 | 3 |
DOI | |
出版状态 | 已出版 - 2021 |
指纹
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Wang, F. M., Li, L. J., Zang, G. W., Deng, T. T., & You, Z. L. (2021). Synthesis, characterization and crystal structures of fluoro-substituted aroylhydrazones with antimicrobial activity. Acta Chimica Slovenica, 63(3), 541-547. https://doi.org/10.17344/ACSI.2020.6051