Study on the chiral separation of anisodamine by high performance capillary electrophoresis

Hong Wang; Junling Gu; Rongji Dai; Ruonong Fu; Hanfang Hu; Tianhui Ding

Study on the chiral separation of anisodamine by high performance capillary electrophoresis

Hong Wang^*, Junling Gu, Rongji Dai, Ruonong Fu, Hanfang Hu, Tianhui Ding

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摘要

Aim: To study the enantiomeric separation of anisodamine. Methods: The factors influencing complexation and resolution were investigated using ß-cyclodextrin (ß-CD) and 2, 6-di-O-carboxymethyl-ß- cyclodextrin (CM-ß-CD) as the chiral selectors by high performance capillary electrophoresis (HPCE). Results: The optimum chiral separation system for anisodamine was established. Conclusion: CM-ß-CD can give a baseline chiral separation for anisodamine and no resolution is found for scopolamine or atropine.

源语言	英语
页（从-至）	380-384
页数	5
期刊	Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology
卷	18
期	3
出版状态	已出版 - 1998

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Wang, H., Gu, J., Dai, R., Fu, R., Hu, H., & Ding, T. (1998). Study on the chiral separation of anisodamine by high performance capillary electrophoresis. Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology, 18(3), 380-384.

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title = "Study on the chiral separation of anisodamine by high performance capillary electrophoresis",

abstract = "Aim: To study the enantiomeric separation of anisodamine. Methods: The factors influencing complexation and resolution were investigated using {\ss}-cyclodextrin ({\ss}-CD) and 2, 6-di-O-carboxymethyl-{\ss}- cyclodextrin (CM-{\ss}-CD) as the chiral selectors by high performance capillary electrophoresis (HPCE). Results: The optimum chiral separation system for anisodamine was established. Conclusion: CM-{\ss}-CD can give a baseline chiral separation for anisodamine and no resolution is found for scopolamine or atropine.",

keywords = "Anisodamine, Chiral separation, High performance capillary electrophoresis, {\ss}-CDs",

author = "Hong Wang and Junling Gu and Rongji Dai and Ruonong Fu and Hanfang Hu and Tianhui Ding",

year = "1998",

language = "English",

volume = "18",

pages = "380--384",

journal = "Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology",

issn = "1001-0645",

publisher = "Beijing Institute of Technology",

number = "3",

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TY - JOUR

T1 - Study on the chiral separation of anisodamine by high performance capillary electrophoresis

AU - Wang, Hong

AU - Gu, Junling

AU - Dai, Rongji

AU - Fu, Ruonong

AU - Hu, Hanfang

AU - Ding, Tianhui

PY - 1998

Y1 - 1998

N2 - Aim: To study the enantiomeric separation of anisodamine. Methods: The factors influencing complexation and resolution were investigated using ß-cyclodextrin (ß-CD) and 2, 6-di-O-carboxymethyl-ß- cyclodextrin (CM-ß-CD) as the chiral selectors by high performance capillary electrophoresis (HPCE). Results: The optimum chiral separation system for anisodamine was established. Conclusion: CM-ß-CD can give a baseline chiral separation for anisodamine and no resolution is found for scopolamine or atropine.

AB - Aim: To study the enantiomeric separation of anisodamine. Methods: The factors influencing complexation and resolution were investigated using ß-cyclodextrin (ß-CD) and 2, 6-di-O-carboxymethyl-ß- cyclodextrin (CM-ß-CD) as the chiral selectors by high performance capillary electrophoresis (HPCE). Results: The optimum chiral separation system for anisodamine was established. Conclusion: CM-ß-CD can give a baseline chiral separation for anisodamine and no resolution is found for scopolamine or atropine.

KW - Anisodamine

KW - Chiral separation

KW - High performance capillary electrophoresis

KW - ß-CDs

UR - http://www.scopus.com/inward/record.url?scp=20444405138&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:20444405138

SN - 1001-0645

VL - 18

SP - 380

EP - 384

JO - Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology

JF - Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology

IS - 3

ER -

Study on the chiral separation of anisodamine by high performance capillary electrophoresis

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