Structure and function analysis of protein HD73-0859 produced by Bacillus thuringiensis

HD73-0859 is a secretory protein from Bacillus thuringiensis (Bt). In this study, its structural feature was analyzed and its function was predicted. The results revealed that HD73-0859 is a peptidase consists of a signal peptide, three well-separated SH3-3 domains and one Peptidase-M23 domain. The peptidase belongs to the M23/37-metallopeptidase family, and might have enzymatic activity to cell wall peptidoglycan and some elastins. This paper improves the understanding of both the protein HD73-0859 and the M23/37-metallopeptidases family, and lays a foundation for further experimental testing and theoretical study.