Seperation and determination of glycyrrhizic acid and liquiritin in licorice using SPE-RP-HPLC

Yu Hong Yu*, Jian Jun Cai, Rong Ji Dai, Yu Lin Deng, Kun Yang, Wei Wei Meng

*此作品的通讯作者

科研成果: 书/报告/会议事项章节会议稿件同行评审

1 引用 (Scopus)

摘要

Glycyrrhizic acid (GA) and liquiritin are the two classes of bioactive components in licorice with known pharmacological effects. In our stud, different methods were compared to separate GA an- d liquiritin. Solid-phase extraction (SPE) method was verified to separate GA and liquiritin effectively. The method is fast, easy, reliable, and inexpensive; especially in the quality control. Moreover, we built a new method to determine Glycyrrhizic acid and liquiritin simultaneously using reversed phase high performance liquid chromatography (RP-HPLC) In the HPLC analyze, gradient elution and two wavelength were used . The regression line for GA was y =15340.6x+12.81, the regression for liquiritin line was y =9269.1x+20.63, The recovery rates were 101.3% and 99.4%; RSD were 1.01% and 0.92%.

源语言英语
主期刊名2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
1856-1860
页数5
DOI
出版状态已出版 - 2007
活动2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007 - Beijing, 中国
期限: 23 5月 200727 5月 2007

出版系列

姓名2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007

会议

会议2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
国家/地区中国
Beijing
时期23/05/0727/05/07

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