TY - GEN
T1 - Separation of 2-HPA by capillary electrophoresis
AU - Dai, Rongji
AU - Yang, Lin
AU - Liu, Wei
AU - Deng, Yulin
PY - 2007
Y1 - 2007
N2 - The enantiomers of three chiral compounds of neural interest, N-(2-heptyl)propargylamine (2-HPA), 2-heptylamine (2-HA) and 2-HPPA were separated analytically using capillary electrophoresis (CE) with cyclodextrin chiral selectors. And dansyl chloride was chosen as the reagent for pre-column derivation to give 2-HPA derivatives. The effects of pH, β-CD concentration, electrolyte concentration and temperature et al. on the chiral separation are investigated in detail. CE is shown to be a simple, efficient, and inexpensive way to separate these three chiral compounds in laboratory.
AB - The enantiomers of three chiral compounds of neural interest, N-(2-heptyl)propargylamine (2-HPA), 2-heptylamine (2-HA) and 2-HPPA were separated analytically using capillary electrophoresis (CE) with cyclodextrin chiral selectors. And dansyl chloride was chosen as the reagent for pre-column derivation to give 2-HPA derivatives. The effects of pH, β-CD concentration, electrolyte concentration and temperature et al. on the chiral separation are investigated in detail. CE is shown to be a simple, efficient, and inexpensive way to separate these three chiral compounds in laboratory.
KW - 2-HPA
KW - Capillary electrophoresis
KW - Chiral separation
KW - Dansylchloride
UR - http://www.scopus.com/inward/record.url?scp=48149105282&partnerID=8YFLogxK
U2 - 10.1109/ICCME.2007.4382074
DO - 10.1109/ICCME.2007.4382074
M3 - Conference contribution
AN - SCOPUS:48149105282
SN - 1424410789
SN - 9781424410781
T3 - 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
SP - 1879
EP - 1882
BT - 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
T2 - 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
Y2 - 23 May 2007 through 27 May 2007
ER -