Separation of 2-HPA by capillary electrophoresis

Rongji Dai; Lin Yang; Wei Liu; Yulin Deng

doi:10.1109/ICCME.2007.4382074

Separation of 2-HPA by capillary electrophoresis

Rongji Dai, Lin Yang, Wei Liu, Yulin Deng^*

^*此作品的通讯作者

Beijing Institute of Technology

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

摘要

The enantiomers of three chiral compounds of neural interest, N-(2-heptyl)propargylamine (2-HPA), 2-heptylamine (2-HA) and 2-HPPA were separated analytically using capillary electrophoresis (CE) with cyclodextrin chiral selectors. And dansyl chloride was chosen as the reagent for pre-column derivation to give 2-HPA derivatives. The effects of pH, β-CD concentration, electrolyte concentration and temperature et al. on the chiral separation are investigated in detail. CE is shown to be a simple, efficient, and inexpensive way to separate these three chiral compounds in laboratory.

源语言	英语
主期刊名	2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
页	1879-1882
页数	4
DOI	https://doi.org/10.1109/ICCME.2007.4382074
出版状态	已出版 - 2007
活动	2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007 - Beijing, 中国期限: 23 5月 2007 → 27 5月 2007

出版系列

姓名	2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007

会议

会议	2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
国家/地区	中国
市	Beijing
时期	23/05/07 → 27/05/07

访问文件

10.1109/ICCME.2007.4382074

其它文件与链接

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引用此

Dai, R., Yang, L., Liu, W., & Deng, Y. (2007). Separation of 2-HPA by capillary electrophoresis. 在 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007 (页码 1879-1882). 文章 4382074 (2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007). https://doi.org/10.1109/ICCME.2007.4382074

@inproceedings{e4ba99dcd85546beb5b95c615a6a1f2d,

title = "Separation of 2-HPA by capillary electrophoresis",

abstract = "The enantiomers of three chiral compounds of neural interest, N-(2-heptyl)propargylamine (2-HPA), 2-heptylamine (2-HA) and 2-HPPA were separated analytically using capillary electrophoresis (CE) with cyclodextrin chiral selectors. And dansyl chloride was chosen as the reagent for pre-column derivation to give 2-HPA derivatives. The effects of pH, β-CD concentration, electrolyte concentration and temperature et al. on the chiral separation are investigated in detail. CE is shown to be a simple, efficient, and inexpensive way to separate these three chiral compounds in laboratory.",

keywords = "2-HPA, Capillary electrophoresis, Chiral separation, Dansylchloride",

author = "Rongji Dai and Lin Yang and Wei Liu and Yulin Deng",

year = "2007",

doi = "10.1109/ICCME.2007.4382074",

language = "English",

isbn = "1424410789",

series = "2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007",

pages = "1879--1882",

booktitle = "2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007",

note = "2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007 ; Conference date: 23-05-2007 Through 27-05-2007",

}

Dai, R, Yang, L, Liu, W & Deng, Y 2007, Separation of 2-HPA by capillary electrophoresis. 在 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007., 4382074, 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007, 页码 1879-1882, 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007, Beijing, 中国, 23/05/07. https://doi.org/10.1109/ICCME.2007.4382074

TY - GEN

T1 - Separation of 2-HPA by capillary electrophoresis

AU - Dai, Rongji

AU - Yang, Lin

AU - Liu, Wei

AU - Deng, Yulin

PY - 2007

Y1 - 2007

N2 - The enantiomers of three chiral compounds of neural interest, N-(2-heptyl)propargylamine (2-HPA), 2-heptylamine (2-HA) and 2-HPPA were separated analytically using capillary electrophoresis (CE) with cyclodextrin chiral selectors. And dansyl chloride was chosen as the reagent for pre-column derivation to give 2-HPA derivatives. The effects of pH, β-CD concentration, electrolyte concentration and temperature et al. on the chiral separation are investigated in detail. CE is shown to be a simple, efficient, and inexpensive way to separate these three chiral compounds in laboratory.

AB - The enantiomers of three chiral compounds of neural interest, N-(2-heptyl)propargylamine (2-HPA), 2-heptylamine (2-HA) and 2-HPPA were separated analytically using capillary electrophoresis (CE) with cyclodextrin chiral selectors. And dansyl chloride was chosen as the reagent for pre-column derivation to give 2-HPA derivatives. The effects of pH, β-CD concentration, electrolyte concentration and temperature et al. on the chiral separation are investigated in detail. CE is shown to be a simple, efficient, and inexpensive way to separate these three chiral compounds in laboratory.

KW - 2-HPA

KW - Capillary electrophoresis

KW - Chiral separation

KW - Dansylchloride

UR - http://www.scopus.com/inward/record.url?scp=48149105282&partnerID=8YFLogxK

U2 - 10.1109/ICCME.2007.4382074

DO - 10.1109/ICCME.2007.4382074

M3 - Conference contribution

AN - SCOPUS:48149105282

SN - 1424410789

SN - 9781424410781

T3 - 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007

SP - 1879

EP - 1882

BT - 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007

T2 - 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007

Y2 - 23 May 2007 through 27 May 2007

ER -

Separation of 2-HPA by capillary electrophoresis

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