Resolution Enhancement Strategies in Photoacoustic Microscopy: A Comprehensive Review

Jinying Zhang*, Yifan Shi, Yexiaotong Zhang, Haoran Liu, Shihao Li, Linglu Liu

*此作品的通讯作者

科研成果: 期刊稿件文献综述同行评审

摘要

Photoacoustic imaging has emerged as a promising modality for medical imaging since its introduction. Photoacoustic microscopy (PAM), which is based on the photoacoustic effect, combines the advantages of both optical and acoustic imaging modalities. PAM facilitates high-sensitivity, high-resolution, non-contact, and non-invasive imaging by employing optical absorption as its primary contrast mechanism. The ability of PAM to specifically image parameters such as blood oxygenation and melanin content makes it a valuable addition to the suite of modern biomedical imaging techniques. This review aims to provide a comprehensive overview of the diverse technical approaches and methods employed by researchers to enhance the resolution of photoacoustic microscopy. Firstly, the fundamental principles of the photoacoustic effect and photoacoustic imaging will be presented. Subsequently, resolution enhancement methods for both acoustic-resolution photoacoustic microscopy (AR-PAM) and optical-resolution photoacoustic microscopy (OR-PAM) will be discussed independently. Finally, the aforementioned resolution enhancement methods for photoacoustic microscopy will be critically evaluated, and the current challenges and future prospects of this technology will be summarized.

源语言英语
文章编号1463
期刊Micromachines
15
12
DOI
出版状态已出版 - 12月 2024

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Zhang, J., Shi, Y., Zhang, Y., Liu, H., Li, S., & Liu, L. (2024). Resolution Enhancement Strategies in Photoacoustic Microscopy: A Comprehensive Review. Micromachines, 15(12), 文章 1463. https://doi.org/10.3390/mi15121463