TY - JOUR
T1 - Research on the 3D image restoration of the wide-field microscope based on the MPMAP
AU - Chen, Hua
AU - Jin, Weiqi
AU - Su, Binghua
AU - Wang, Xia
AU - Bai, Tingzhu
PY - 2006
Y1 - 2006
N2 - A new method is proposed for the 3D (three-dimensional) image restoration of the wide-field microscope based on the MPMAP algorithm (Poisson-MAP Super-resolution image restoration algorithm with Markov constraint) according to the 3D features of the microscopic image. The neighborhood of the Markov random field in MPMAP algorithm is extended to 3D, and the regularization parameter α of the bound term in MPMAP is simplified. As a result, the restoration of 3D image of wide-field microscope is achieved, and the more perfect effect of the image restoration is got. When images within noise are restored by different value α, different attainable resolution and signal-to-noise ratio (SNR) in the restored image. Experiment results show that it is necessary to select appropriately value of α, and take tradeoff between resolution and SNR in the restored image so that the more perfect effect of the image restoration is got.
AB - A new method is proposed for the 3D (three-dimensional) image restoration of the wide-field microscope based on the MPMAP algorithm (Poisson-MAP Super-resolution image restoration algorithm with Markov constraint) according to the 3D features of the microscopic image. The neighborhood of the Markov random field in MPMAP algorithm is extended to 3D, and the regularization parameter α of the bound term in MPMAP is simplified. As a result, the restoration of 3D image of wide-field microscope is achieved, and the more perfect effect of the image restoration is got. When images within noise are restored by different value α, different attainable resolution and signal-to-noise ratio (SNR) in the restored image. Experiment results show that it is necessary to select appropriately value of α, and take tradeoff between resolution and SNR in the restored image so that the more perfect effect of the image restoration is got.
KW - 3D continuation of the neighborhood
KW - 3D wide-field microscopic image
KW - Image restoration
KW - MPMAP algorithm
KW - Markov random field
KW - Regularization parameter α
UR - http://www.scopus.com/inward/record.url?scp=33645164247&partnerID=8YFLogxK
U2 - 10.1117/12.667140
DO - 10.1117/12.667140
M3 - Conference article
AN - SCOPUS:33645164247
SN - 0277-786X
VL - 6026
JO - Proceedings of SPIE - The International Society for Optical Engineering
JF - Proceedings of SPIE - The International Society for Optical Engineering
M1 - 60260L
T2 - ICO20: Biomedical Optics
Y2 - 21 August 2005 through 26 August 2005
ER -