Progress of new strategies on screening of targeting peptides and applications in tumor immunotherapy

Malignant tumor has threatened human's health. Along with the deep understanding of the mechanism of tumor immune cycle, tumor immune diagnosis and therapy have become the research hot spot. Among all the theranostic reagents, peptides have good affinity, high specificity, good biocompatibility, ease of modification and so on. Peptide-based reagents have broad application prospects and great potential in tumor immune diagnosis and therapy. This review summarizes from the aspects of some new methods and new strategies on targeting peptide probes screening and construction. Furthermore, we focus on some research progress on targeting-peptide-based tumor immunol imaging and peptide-based immune checkpoint therapy.