PreTP-EL: Prediction of therapeutic peptides based on ensemble learning

Yichen Guo, Ke Yan, Hongwu Lv, Bin Liu*

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

42 引用 (Scopus)

摘要

Therapeutic peptides are important for understanding the correlation between peptides and their therapeutic diagnostic potential. The therapeutic peptides can be further divided into different types based on therapeutic function sharing different characteristics. Although some computational approaches have been proposed to predict different types of therapeutic peptides, they failed to accurately predict all types of therapeutic peptides. In this study, a predictor called PreTP-EL has been proposed via employing the ensemble learning approach to fuse the different features and machine learning techniques in order to capture the different characteristics of various therapeutic peptides. Experimental results showed that PreTP-EL outperformed other competing methods. Availability and implementation: A user-friendly web-server of PreTP-EL predictor is available at http://bliulab.net/PreTP-EL.

源语言英语
文章编号bbab358
期刊Briefings in Bioinformatics
22
6
DOI
出版状态已出版 - 1 11月 2021

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