@article{d11876915a6f40d2a600c4ce9d6d6c7e,
title = "Pd/Zn Co-catalyzed Asymmetric Ring-Opening Reactions of Aza/Oxabicyclic Alkenes with Oximes",
abstract = "An application of various oximes as nucleophiles in the asymmetric ring-opening (ARO) reaction of aza/oxabicyclic alkenes resulting in cis-ARO products has been developed. The reaction was co-catalyzed by Pd(OAc)2 and Zn(OTf)2 with (R)-DIFLUORPHOS as the chiral ligand. This methodology exhibits broad substrate scope, functional group tolerance with high enantioselectivity. A synthetic application of this method has been demonstrated.",
keywords = "asymmetric catalysis, asymmetric synthesis, norbornadienes, oximes, ring-opening reactions",
author = "Guoli Shen and Ruhima Khan and Fan Yang and Yong Yang and Dongdong Pu and Yang Gao and Yong Zhan and Yang Luo and Baomin Fan",
note = "Publisher Copyright: {\textcopyright} 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",
year = "2019",
month = jan,
doi = "10.1002/ajoc.201800569",
language = "English",
volume = "8",
pages = "97--102",
journal = "Asian Journal of Organic Chemistry",
issn = "2193-5807",
publisher = "Wiley - VCH Verlag GmbH & CO. KGaA",
number = "1",
}