Microdevice for magnetic cell separation simple fabrication and simulation analysis

O. Saeed, Yulin Deng

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

Rare cells separation from blood as in circulating tumor cells (CTCs) isolation and other cells from blood has fetal importance in disease monitoring and treatment. Here we study a method for cancer cells separation from patient blood or buffer sample by magnetic focusing technique. Magnetic and drag forces computational simulation and calculations been presented. The microfluidic device chractrization, was carried by using COMSOL Multiphysics 4.3a modeling software (COMSOL, Inc.) The simulation was carried out in two stages including magnetic field generated from the permanent magnet positioned at a specific distance from the microchannel wall and the cell/particle tracing for cell separation verifications. Separation with 98% purity and efficiency of the unwanted particle was achieved 0.105m/s velocity. Considering the results achieved and cancer cells size about 15 μm, our proposed microchannel device is a good candidate for cancer cells separation from blood/buffer.

源语言英语
主期刊名IEEE International Conference on Power, Control, Signals and Instrumentation Engineering, ICPCSI 2017
出版商Institute of Electrical and Electronics Engineers Inc.
2006-2010
页数5
ISBN(电子版)9781538608135
DOI
出版状态已出版 - 20 6月 2018
活动2017 IEEE International Conference on Power, Control, Signals and Instrumentation Engineering, ICPCSI 2017 - Chennai, 印度
期限: 21 9月 201722 9月 2017

出版系列

姓名IEEE International Conference on Power, Control, Signals and Instrumentation Engineering, ICPCSI 2017

会议

会议2017 IEEE International Conference on Power, Control, Signals and Instrumentation Engineering, ICPCSI 2017
国家/地区印度
Chennai
时期21/09/1722/09/17

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