摘要
We developed a double-sided micro-well array microfluidic chip which consists of three parts: microfluidic channel, cell trapping array and cell lysate collecting chamber. We integrated single cell trapping, identification and in situ cell lysis in this microfluidic chip to differentiate Epidermal Growth Factor Receptor (EGFR)-expressed cancer cells from normal cells, for detecting not only the existence of EGFR expression, but also various mutation types at single cell level.
| 源语言 | 英语 |
|---|---|
| 主期刊名 | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
| 出版商 | Chemical and Biological Microsystems Society |
| 页 | 206-207 |
| 页数 | 2 |
| ISBN（电子版） | 9780979806490 |
| 出版状态 | 已出版 - 2016 |
| 已对外发布 | 是 |
| 活动 | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, 爱尔兰 期限: 9 10月 2016 → 13 10月 2016 |
出版系列
| 姓名 | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
|---|
会议
| 会议 | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
|---|---|
| 国家/地区 | 爱尔兰 |
| 市 | Dublin |
| 时期 | 9/10/16 → 13/10/16 |
指纹
探究 'Micro-well array based genetic determination of EGFR mutation at single-cell level' 的科研主题。它们共同构成独一无二的指纹。引用此
Li, R., Zhou, M., Li, J., Zhang, W., Wang, Z., Wei, Z., & Hu, Z. (2016). Micro-well array based genetic determination of EGFR mutation at single-cell level. 在 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (页码 206-207). (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016). Chemical and Biological Microsystems Society.