Lattice Boltzmann study of micro branch array of crossflow filtration for fluid partitioning

Shiyu Cheng, Yuanqing Xu*, Xiaoying Tang, Rui Yang

*此作品的通讯作者

科研成果: 书/报告/会议事项章节会议稿件同行评审

1 引用 (Scopus)

摘要

In the past decade, a flurry of new blood cells separation methods based microfluidic chip technology has emerged to address clinical diagnosis and biological research. The crossflow-based filtration separation method, because of its simple working principle and effectively overcoming the chip clogging problem, is gradually developing as an attractive solution for blood cells separation. In order to investigate and optimize the structure of a crossflow-based separator for blood cells, we studied how the tilt angle of the micro branch channel in the pillar array affects the fluid partitioning of low Reynolds number using Lattice Boltzmann (LBM) method. The reliability of using LBM to solve the flow of fluid of low Reynolds number is validated by the simulation of Poiseuille flow, and then a model of the branch channel, which mainly focuses on 4 different tilt angle (30°, 45°, 60°, 90°), is built to simulate. For far upstream and downstream in the main channel, and downstream in the side branch array channels, the fluid velocity profiles are assumed to adopt those of unidirectional Poiseuille flow with prescribed flow rates. The results show that the angle of inclination, with other conditions constant, will significantly influence the partition of fluid in the main channel and side branch array channels. Generally the larger the tilt angle is, the larger the rate flow in the branch array channel is, or vice versa.

源语言英语
主期刊名2013 ICME International Conference on Complex Medical Engineering, CME 2013
586-589
页数4
DOI
出版状态已出版 - 2013
活动2013 7th ICME International Conference on Complex Medical Engineering, CME 2013 - Beijing, 中国
期限: 25 5月 201328 5月 2013

出版系列

姓名2013 ICME International Conference on Complex Medical Engineering, CME 2013

会议

会议2013 7th ICME International Conference on Complex Medical Engineering, CME 2013
国家/地区中国
Beijing
时期25/05/1328/05/13

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