TY - JOUR
T1 - Isolation and structural identification of lignans from Dregea sinensis Hemsl
AU - Jia, Shao Hua
AU - Lü, Fang
AU - Dai, Rong Ji
AU - Meng, Wei Wei
AU - Chen, Yan
AU - Deng, Yu Lin
N1 - Publisher Copyright:
©, 2015, Beijing Institute of Technology. All right reserved.
PY - 2015/3/1
Y1 - 2015/3/1
N2 - In order to study the chemical constituents of Dregea sinensis Hemsl, five lignans were isolated from the roots of Dregea sinensis Hemsl by AB-8 macroporous resin column, silica gel column, Sephadex LH-20 column and semi-preparative HPLC. On the basis of 1D and 2D NMR data and MS analyses, their structures were identified as 4', 4″-dihydroxy-3,3', 3″, 5,5', 5″-hexamethoxy-7,9':7',9-diepoxy-4,8″-oxy-8,8'-sesquineolignan-7″, 9″-diol (1), 4',4″-dihydroxy-3,3', 3″, 5, 5'-pentamethoxy-7,9':7', 9-diepoxy-4,8″-oxy-8,8'-sesquineo-lignan-7″, 9″-diol (2), (+)-isolariciresinol (3), erythro-guaiacylycerol-β-O-4'-coniferyl alcohol (4), diasyringaresinol (5). These compounds were isolated from this plant for the first time.
AB - In order to study the chemical constituents of Dregea sinensis Hemsl, five lignans were isolated from the roots of Dregea sinensis Hemsl by AB-8 macroporous resin column, silica gel column, Sephadex LH-20 column and semi-preparative HPLC. On the basis of 1D and 2D NMR data and MS analyses, their structures were identified as 4', 4″-dihydroxy-3,3', 3″, 5,5', 5″-hexamethoxy-7,9':7',9-diepoxy-4,8″-oxy-8,8'-sesquineolignan-7″, 9″-diol (1), 4',4″-dihydroxy-3,3', 3″, 5, 5'-pentamethoxy-7,9':7', 9-diepoxy-4,8″-oxy-8,8'-sesquineo-lignan-7″, 9″-diol (2), (+)-isolariciresinol (3), erythro-guaiacylycerol-β-O-4'-coniferyl alcohol (4), diasyringaresinol (5). These compounds were isolated from this plant for the first time.
KW - Asclepiadaceae
KW - Constituent
KW - Dregea sinensis Hemsl
KW - Lignans
KW - Structure identification
UR - http://www.scopus.com/inward/record.url?scp=84929461633&partnerID=8YFLogxK
U2 - 10.15918/j.tbit1001-0645.2015.03.021
DO - 10.15918/j.tbit1001-0645.2015.03.021
M3 - Article
AN - SCOPUS:84929461633
SN - 1001-0645
VL - 35
SP - 326
EP - 330
JO - Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology
JF - Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology
IS - 3
ER -