Investigation of the reaction of o-aminonitriles with ketones: A new modification of Friedländer reaction and structures of its products

Jiarong Li*, Lijun Zhang, Daxin Shi, Qing Li, Dong Wang, Chunxia Wang, Qi Zhang, Ling Zhang, Yanqiu Fan

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

46 引用 (Scopus)

摘要

A new modification of the Friedländer reaction is described and the new byproduct obtained from the reaction of o-aminonitriles and ketones was found to be 2,3-dihydroquinazolin-4(1H)-one. The mechanism probably involved the formation of an intermediate oxazine, via the Pinner reaction and its transformation into new products via the Dimroth rearrangement.

源语言英语
页(从-至)233-236
页数4
期刊Synlett
2
DOI
出版状态已出版 - 22 1月 2008

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