Highly stereoselective synthesis of trisubstituted cyclohexanols using a guanidine-catalyzed tandem Henry-Michael reaction

Qipu Dai; Huicai Huang; John Cong-Gui Zhao

doi:10.1021/jo4001806

Highly stereoselective synthesis of trisubstituted cyclohexanols using a guanidine-catalyzed tandem Henry-Michael reaction

Qipu Dai, Huicai Huang, John Cong-Gui Zhao^*

^*此作品的通讯作者

科研成果: 期刊稿件 › 文章 › 同行评审

27 引用（Scopus）

摘要

A highly diastereoselective (dr >99:1) and enantioselective (ee value up to 98%) synthesis of trisubstituted cyclohexanols was achieved by using a tandem Henry - Michael reaction between nitromethane and 7-oxo-hept-5-enals catalyzed by the Misaki-Sugimura guanidine.

源语言	英语
页（从-至）	4153-4157
页数	5
期刊	Journal of Organic Chemistry
卷	78
期	8
DOI	https://doi.org/10.1021/jo4001806
出版状态	已出版 - 19 4月 2013
已对外发布	是

访问文件

10.1021/jo4001806

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{b0e0403b53cf43978da83e522a5413ac,

title = "Highly stereoselective synthesis of trisubstituted cyclohexanols using a guanidine-catalyzed tandem Henry-Michael reaction",

abstract = "A highly diastereoselective (dr >99:1) and enantioselective (ee value up to 98%) synthesis of trisubstituted cyclohexanols was achieved by using a tandem Henry - Michael reaction between nitromethane and 7-oxo-hept-5-enals catalyzed by the Misaki-Sugimura guanidine.",

author = "Qipu Dai and Huicai Huang and {Cong-Gui Zhao}, John",

year = "2013",

month = apr,

day = "19",

doi = "10.1021/jo4001806",

language = "English",

volume = "78",

pages = "4153--4157",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "8",

}

TY - JOUR

T1 - Highly stereoselective synthesis of trisubstituted cyclohexanols using a guanidine-catalyzed tandem Henry-Michael reaction

AU - Dai, Qipu

AU - Huang, Huicai

AU - Cong-Gui Zhao, John

PY - 2013/4/19

Y1 - 2013/4/19

N2 - A highly diastereoselective (dr >99:1) and enantioselective (ee value up to 98%) synthesis of trisubstituted cyclohexanols was achieved by using a tandem Henry - Michael reaction between nitromethane and 7-oxo-hept-5-enals catalyzed by the Misaki-Sugimura guanidine.

AB - A highly diastereoselective (dr >99:1) and enantioselective (ee value up to 98%) synthesis of trisubstituted cyclohexanols was achieved by using a tandem Henry - Michael reaction between nitromethane and 7-oxo-hept-5-enals catalyzed by the Misaki-Sugimura guanidine.

UR - http://www.scopus.com/inward/record.url?scp=84876591560&partnerID=8YFLogxK

U2 - 10.1021/jo4001806

DO - 10.1021/jo4001806

M3 - Article

AN - SCOPUS:84876591560

SN - 0022-3263

VL - 78

SP - 4153

EP - 4157

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 8

ER -

Highly stereoselective synthesis of trisubstituted cyclohexanols using a guanidine-catalyzed tandem Henry-Michael reaction

摘要

访问文件

其它文件与链接

指纹

引用此