@inproceedings{7919d6ca97a4460e802fc84518f968a4,
title = "High throughput synthesis of oligonucleotide utilizing inkjet printer and micro-reactor array filled with robust opal",
abstract = "Oligonucleotide synthesis with high throughput is a current challenge in modern life science. This paper presents a high throughput oligonucleotide synthesizer based on inkjet printer and micro-reactor array chip. Integration of the micro-reactor array filled with robust opal and a modified commercial inkjet printer enables the synthesis of 100 different oligonucleotides on a 20mm×20mm chip. Utilizing the prototype system, we successfully synthesized oligonucleotides of 6 monomers at a yield of about 100 pmol. This oligonucleotide synthesizer can be potentially used for genomic applications, which require tons of probes and primers in a short time.",
keywords = "High throughput, Inkjet printer, Micro-reactor, Oligonucleotide synthesizer, Opal",
author = "H. Li and Y. Huang and Yu, {H. Q.} and Y. Ma and Tang, {C. Y.} and Wei, {Z. W.} and Liang, {Z. C.} and W. Wang and Yang, {Z. J.} and Li, {Z. H.}",
year = "2013",
language = "English",
isbn = "9781632666246",
series = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
publisher = "Chemical and Biological Microsystems Society",
pages = "1242--1244",
booktitle = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
note = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 ; Conference date: 27-10-2013 Through 31-10-2013",
}