Graphene-based nanomaterials for cancer therapy and anti-infections

Yan Wang, Juan Li, Xiaobin Li, Jinping Shi, Zhaotan Jiang, Can Yang Zhang*

*此作品的通讯作者

科研成果: 期刊稿件文献综述同行评审

56 引用 (Scopus)

摘要

Graphene-based nanomaterials (GBNMs) has been thoroughly investigated and extensively used in many biomedical fields, especially cancer therapy and bacteria-induced infectious diseases treatment, which have attracted more and more attentions due to the improved therapeutic efficacy and reduced reverse effect. GBNMs, as classic two-dimensional (2D) nanomaterials, have unique structure and excellent physicochemical properties, exhibiting tremendous potential in cancer therapy and bacteria-induced infectious diseases treatment. In this review, we first introduced the recent advances in development of GBNMs and GBNMs-based treatment strategies for cancer, including photothermal therapy (PTT), photodynamic therapy (PDT) and multiple combination therapies. Then, we surveyed the research progress of applications of GBNMs in anti-infection such as antimicrobial resistance, wound healing and removal of biofilm. The mechanism of GBNMs was also expounded. Finally, we concluded and discussed the advantages, challenges/limitations and perspective about the development of GBNMs and GBNMs-based therapies. Collectively, we think that GBNMs could be potential in clinic to promote the improvement of cancer therapy and infections treatment.

源语言英语
页(从-至)335-349
页数15
期刊Bioactive Materials
14
DOI
出版状态已出版 - 8月 2022

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