Glucose dispersion measurement using white-light LCI

We measured second order dispersion of glucose solution using a Michelson Low Coherent Interferometer (LCI). Three different glucose concentrations: 20mg/dl (hypoglycemia), l00mg/dl (normal level), and 500mg/dl (hyperglycemia) are investigated over the wavelength range O.5μm to 0.85μm, and the investigation shows that different concentrations are associated with different second-order dispersions. The second-order dispersions for wavelengths from 0.55μm to 0.8μm are determined by Fourier analysis of the interferogram. This approach can be applied to measure the second-order dispersion for distinguishing the different glucose concentrations. It can be considered as a potentially noninvasive method to determine glucose concentration in human eye. A brief discussion is presented in this poster as well.