TY - GEN
T1 - Genome-wide Association study for glaucoma
AU - Liu, Jiang
AU - Zhang, Zhuo
AU - Chin, Shu Min
AU - Teo, Yun Lin Penny
AU - Wong, Wing Kee
AU - Tan, Ngan Meng
AU - Lim, Joo Hwee
AU - Lu, Shijian
AU - Li, Huiqi
AU - Wong, Tien Yin
PY - 2009
Y1 - 2009
N2 - The Genome-Wide Association (GWA) study is the latest approach in the development of genetic studies and is renowned for its widespread success in identifying disease variants within the genome for various common diseases. It is a highly popular study amongst geneticists worldwide, evident from the numerous GWA studies conducted in laboratories all over the world. This paper introduces various GWA study designs currently recognized, including other aspects such as the software tools and its progress thus far. Especially, the paper reviews the genetic studies for glaucoma, an ocular disease which can lead to irreversible and permanent vision loss. Glaucomatous progression can be slowed or even halted if detected early; however, genetic information on glaucoma has not been well established yet. Therefore, by conducting a GWA study on glaucoma to find comprehensive associated genetic variants, the early detection of glaucoma through GWA may finally be seen as a possibility.
AB - The Genome-Wide Association (GWA) study is the latest approach in the development of genetic studies and is renowned for its widespread success in identifying disease variants within the genome for various common diseases. It is a highly popular study amongst geneticists worldwide, evident from the numerous GWA studies conducted in laboratories all over the world. This paper introduces various GWA study designs currently recognized, including other aspects such as the software tools and its progress thus far. Especially, the paper reviews the genetic studies for glaucoma, an ocular disease which can lead to irreversible and permanent vision loss. Glaucomatous progression can be slowed or even halted if detected early; however, genetic information on glaucoma has not been well established yet. Therefore, by conducting a GWA study on glaucoma to find comprehensive associated genetic variants, the early detection of glaucoma through GWA may finally be seen as a possibility.
UR - http://www.scopus.com/inward/record.url?scp=77950843601&partnerID=8YFLogxK
U2 - 10.1109/ICBPE.2009.5384083
DO - 10.1109/ICBPE.2009.5384083
M3 - Conference contribution
AN - SCOPUS:77950843601
SN - 9781424447640
T3 - 2nd International Conference on Biomedical and Pharmaceutical Engineering, ICBPE 2009 - Conference Proceedings
BT - 2nd International Conference on Biomedical and Pharmaceutical Engineering, ICBPE 2009 - Conference Proceedings
T2 - 2nd International Conference on Biomedical and Pharmaceutical Engineering, ICBPE 2009
Y2 - 2 December 2009 through 4 December 2009
ER -