@article{cd9061065a634ef9be804383400df117,
title = "Enantioselective Addition of Pyrazoles to Dienes**",
abstract = "We report the first enantioselective addition of pyrazoles to 1,3-dienes. Secondary and tertiary allylic pyrazoles can be generated with excellent regioselectivity. Mechanistic studies support a pathway distinct from previous hydroaminations: a Pd0-catalyzed ligand-to-ligand hydrogen transfer (LLHT). This hydroamination tolerates a range of functional groups and advances the field of diene hydrofunctionalization.",
keywords = "1,3-diene, Pd-catalysis, enantioselectivity, hydroamination, pyrazole",
author = "Jiu, {Alexander Y.} and Slocumb, {Hannah S.} and Yeung, {Charles S.} and Yang, {Xiao Hui} and Dong, {Vy M.}",
note = "Publisher Copyright: {\textcopyright} 2021 Wiley-VCH GmbH",
year = "2021",
month = sep,
day = "1",
doi = "10.1002/anie.202105679",
language = "English",
volume = "60",
pages = "19660--19664",
journal = "Angewandte Chemie - International Edition",
issn = "1433-7851",
publisher = "John Wiley and Sons Ltd",
number = "36",
}