Efficient constructions of the four different thienopyrimidinone skeletons via various cyclocondensation of o-aminothienonitrile with carbonyl compounds

Junjuan Yang, Daxin Shi, Kai Zhang, Zhangtao Zhao, Fadong Qiu, Yujiao Bi, Qi Zhang, Jiarong Li*

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

1 引用 (Scopus)

摘要

A series of new thienopyrimidinone derivatives were synthesized via a novel, straightforward and efficient tandem cyclocondensation of o-aminothienonitrile 1 and carbonyl compounds 2 in different conditions. The synthesized four thienopyrimidinone skeletons were thieno[2,3-d]pyrimidinone 3, tert-hydroxythieno[2,3-d]pyrimidinone 4, symmetrical tetracycle thienothiophenepyrimidone 5 and thienopyrimidine 6 respectively. Their plausible mechanisms were proposed. The properties of compound 5 were investigated.

源语言英语
页(从-至)866-885
页数20
期刊Heterocycles
92
5
DOI
出版状态已出版 - 2016

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