Distinguishing of tumor cell-targeting peptide ligands through a color-encoding microarray

Zihua Wang; Weizhi Wang; Lingling Geng; Zhiyuan Hu

doi:10.1039/c5lc01010a

Distinguishing of tumor cell-targeting peptide ligands through a color-encoding microarray

Zihua Wang, Weizhi Wang^*, Lingling Geng, Zhiyuan Hu

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National Center for Nanoscience and Technology

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5 引用（Scopus）

摘要

A silicon-based microarray system was constructed to discover the affinity peptides and to distinguish the specific peptides from a high throughput library. Using a color-encoding strategy, in situ peptide distinguishing between HER1 ligands and HER2 ligands was achieved. Novel affinity peptide sequences H1P (HER1 ligand) and H2P (HER2 ligand) were determined with nmol affinity.

源语言	英语
页（从-至）	4512-4516
页数	5
期刊	Lab on a Chip
卷	15
期	24
DOI	https://doi.org/10.1039/c5lc01010a
出版状态	已出版 - 2015
已对外发布	是

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10.1039/c5lc01010a

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title = "Distinguishing of tumor cell-targeting peptide ligands through a color-encoding microarray",

abstract = "A silicon-based microarray system was constructed to discover the affinity peptides and to distinguish the specific peptides from a high throughput library. Using a color-encoding strategy, in situ peptide distinguishing between HER1 ligands and HER2 ligands was achieved. Novel affinity peptide sequences H1P (HER1 ligand) and H2P (HER2 ligand) were determined with nmol affinity.",

author = "Zihua Wang and Weizhi Wang and Lingling Geng and Zhiyuan Hu",

note = "Publisher Copyright: {\textcopyright} 2015 The Royal Society of Chemistry.",

year = "2015",

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T1 - Distinguishing of tumor cell-targeting peptide ligands through a color-encoding microarray

AU - Wang, Zihua

AU - Wang, Weizhi

AU - Geng, Lingling

AU - Hu, Zhiyuan

PY - 2015

Y1 - 2015

N2 - A silicon-based microarray system was constructed to discover the affinity peptides and to distinguish the specific peptides from a high throughput library. Using a color-encoding strategy, in situ peptide distinguishing between HER1 ligands and HER2 ligands was achieved. Novel affinity peptide sequences H1P (HER1 ligand) and H2P (HER2 ligand) were determined with nmol affinity.

AB - A silicon-based microarray system was constructed to discover the affinity peptides and to distinguish the specific peptides from a high throughput library. Using a color-encoding strategy, in situ peptide distinguishing between HER1 ligands and HER2 ligands was achieved. Novel affinity peptide sequences H1P (HER1 ligand) and H2P (HER2 ligand) were determined with nmol affinity.

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U2 - 10.1039/c5lc01010a

DO - 10.1039/c5lc01010a

M3 - Article

C2 - 26530232

AN - SCOPUS:84948405307

SN - 1473-0197

VL - 15

SP - 4512

EP - 4516

JO - Lab on a Chip

JF - Lab on a Chip

IS - 24

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Distinguishing of tumor cell-targeting peptide ligands through a color-encoding microarray

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