TY - JOUR
T1 - Creation of Nonspherical Microparticles through Osmosis-Driven Arrested Coalescence of Microfluidic Emulsions
AU - Feng, Kai
AU - Gao, Ning
AU - Zhang, Wanlin
AU - Zhou, Kang
AU - Dong, Hao
AU - Wang, Peng
AU - Tian, Li
AU - He, Guokang
AU - Li, Guangtao
N1 - Publisher Copyright:
© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
PY - 2020/3/1
Y1 - 2020/3/1
N2 - Droplet-based microfluidics enable the production of emulsions and microparticles with spherical shapes, but the high-throughput fabrication of nonspherical emulsions and microparticles still remains challenging because interfacial tension plays a dominant role during preparation. Herein, ionic liquids (ILs) containing salts, which possess sufficient osmotic pressure to realize water transport and phase separation, are introduced as inner cores of oil-in-oil-in-water double emulsions and it is shown that nonspherical emulsions can be constructed by osmosis-driven arrested coalescence of inner cores. Subsequently, ultraviolet polymerization of the nonspherical emulsions leads to nonspherical microparticles. By tailoring the number, composition, and size of inner cores as well as coalescence time, a variety of nonspherical shapes such as dumbbell, rod, spindle, snowman, tumbler, three-pointed star, triangle, and scalene triangle are created. Importantly, benefitting from excellent solvency of ILs, this system can serve as a general platform to produce nonspherical microparticles made from different materials. Moreover, by controlling the osmotic pressure, programmed coalescence of inner cores in double emulsions is realizable, which indicates the potential to build microreactors. Thus, a simple and high-throughput strategy to create nonspherical microparticles with arrested coalescence shapes is developed for the first time and can be further used to construct novel materials and microreactors.
AB - Droplet-based microfluidics enable the production of emulsions and microparticles with spherical shapes, but the high-throughput fabrication of nonspherical emulsions and microparticles still remains challenging because interfacial tension plays a dominant role during preparation. Herein, ionic liquids (ILs) containing salts, which possess sufficient osmotic pressure to realize water transport and phase separation, are introduced as inner cores of oil-in-oil-in-water double emulsions and it is shown that nonspherical emulsions can be constructed by osmosis-driven arrested coalescence of inner cores. Subsequently, ultraviolet polymerization of the nonspherical emulsions leads to nonspherical microparticles. By tailoring the number, composition, and size of inner cores as well as coalescence time, a variety of nonspherical shapes such as dumbbell, rod, spindle, snowman, tumbler, three-pointed star, triangle, and scalene triangle are created. Importantly, benefitting from excellent solvency of ILs, this system can serve as a general platform to produce nonspherical microparticles made from different materials. Moreover, by controlling the osmotic pressure, programmed coalescence of inner cores in double emulsions is realizable, which indicates the potential to build microreactors. Thus, a simple and high-throughput strategy to create nonspherical microparticles with arrested coalescence shapes is developed for the first time and can be further used to construct novel materials and microreactors.
KW - arrested coalescence
KW - ionic liquids
KW - microfluidic emulsions
KW - nonspherical microparticles
KW - osmotic pressure
UR - http://www.scopus.com/inward/record.url?scp=85073807397&partnerID=8YFLogxK
U2 - 10.1002/smll.201903884
DO - 10.1002/smll.201903884
M3 - Article
C2 - 31512376
AN - SCOPUS:85073807397
SN - 1613-6810
VL - 16
JO - Small
JF - Small
IS - 9
M1 - 1903884
ER -